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    Is there hope for degenerative disk disease?

    Although I had already 2 prior surgeries including a 3-level fusion (L4-L5-S1) performed in 2017 due to emergency Cauda Equina Compression in my record, I needed to have a 3rd one done due to some new neurological symptoms, including pain (lumbar, sciatica et.al.). With that, I did some...
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    Anyone combine injections and cream? How do you feel?

    wow, thanks a lot for your response. You went above and beyond what I was expecting.... Just to clarify a few things and confirm what you found in previous posts: 1) I am used to use a low dose of AI from the get go from Defy: - 70mg Test - twice per week - Some HCG which I stopped due to...
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    Anyone combine injections and cream? How do you feel?

    You are right, I will gather my previous protocols with lab work and start my own thread. I only asked you here because it was the first time that I read about a relationship between Testosterone levels with Cortisol levels. Until now, I was taking my medications but always thinking "what's...
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    Anyone combine injections and cream? How do you feel?

    Thanks for your reply! My thyroid numbers are great, my Test levels are high, but I am still sleepy.... I have been asking for help to the medical community for 4 years with no one listening to me other than prescribing stimulants/antidepressants. And they didn't help unfortunately...
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    Anyone combine injections and cream? How do you feel?

    Could you please elaborate on this?? My cortisol is low... ultra low to the point that I only wake up after 2PM. Hydrocortisone helps a lot but at what dose does it become “dangerous”?
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    Issues with Testosterone Cream -- anyone else?

    I take 25mg to try to maintain the muscle mass on one of my legs. Honestly I would need a higher dose but at 25mg/day, it only tanks my HDL cholesterol. My liver enzymes are not affected much if at all so at the doses you mentioned, I would think that the side-effects would be very mild ...
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    Issues with Testosterone Cream -- anyone else?

    No problem! My oxandrolone dose is 25mg/day and it is part of my HRT protocol ... I mean, Dr. Saya prescribes it but like I said, it is due to a wasting problem on my leg (it wouldn’t be necessary for my TRT)
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    Issues with Testosterone Cream -- anyone else?

    That’s a clever solution. I will discuss that with Dr. Saya... or maybe, since I barely aromatize on the cream, use the cream as a base and titrate Tcyp and HCG. Or even use Oxandrolone as a base (which I am prescribed for a wasting problem on my leg due to a spinal chord injury) instead of...
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    Issues with Testosterone Cream -- anyone else?

    You may be onto something about the DHT vs E2 on the cream. I am still struggling with low E2 unless I use HCG which is almost impossible to dial in. I have a consult with Defy in about 2 weeks... hopefully they can figure something out like adding Tcyp for example. Let’s see... Thanks for...
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    Issues with Testosterone Cream -- anyone else?

    Could you please elaborate more on this? I have been on several protocols using injections and my E2 have always had to be controlled by AIs to manage symptoms. Upon changing my protocol to T cream on my shoulders, E2 was undetected (TT=400s). Then started to apply 150mg to my belly, my E2...
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    Antidepressants

    Hi L2S, Hope you are doing better by now! In case you didn't start the medication yet, I would definitely talk to the doctor to add Bupropion XL (300mg once a day) like others suggested to the SSRI. SSRI's are great for anxiety and panic attacks but not that great for depression which involves...
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