Recent content by Dwhit

has anyone ever injected testosterone based on a sliding scale? diabetics will often inject insulin on a sliding scale based upon their daily blood glucose values, and their diet/exercise each day. what about injecting testosterone on a sliding scale based upon symptoms? after 5 years on the...

Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug How does this cream work locally given that tamoxifen requires hepatic activation?

This is an issue I've been struggling with for the past couple years. I used to be able to tolerate total testosterone levels of around 1000. But I just turned 50, and now I try to keep my level around 600 to 700. I also stopped HCG since that seemed to make things worse. I also switched to...

Blobs of fat are not meant to be in the bloodstream, and can be harmful when they are. For example, fat embolization syndrome is a well-known sequela of orthopedic injuries. Someone breaks their femur, and little pieces of the marrow enter the bloodstream, showering the lungs with numerous...

I mentioned in my original post that esterified testosterone is not affected by aromatase. I've seen Dr. Saya mention this, and I've seen it posted a few times on various forums, but I just looked, and I cannot find any research to back this up. On the contrary, I found reference to the fact...

Here is an article that lends support to the idea that there is no difference between subq and IM injections in terms of local estrogen conversion:

Could it be that a lot of guys who think they are injecting intramuscularly in the gluteal region are actually injecting subcutaneously?

Don't dis broscience, bro. The average guy on this forum knows more than most of the docs out there prescribing trt. I was first managed by a urologist colleague of mine at a major academic university. His protocol for me was 3000 iu HCG 3x/wk and anastrozole 1mg qday. He didn't even monitor...

Yeah, I have great respect for Dr. Crisler. In a recent interview posted on YouTube, he talked about how 95% of his guys are very happy having switched to subcutaneous, but a small minority do not do well, and it's not clear why. Interestingly, in that same interview, he talked about the...

Yeah, I like to think about these things having a physiology background myself. Sorry if it was overkill. I'm not sitting in a room pulling my hair out over what to do next for myself. I realize that the bottom line is that every protocol has its trade offs, and every individual is different...

Thanks! Were you using an AI at the time?

Here are a couple references and a screencap from a textbook: http://www.sciencedirect.com/science/article/pii/0039128X83900624 https://www.ncbi.nlm.nih.gov/pubmed/26690043

Having found that I have a lowish SHBG (22; normal range 16.5-55.9), and having what I believe to be related clincal symptoms, I've decided to follow the advice of some members of this forum, and increase the frequency of my injections from 2x/wk to daily injections. What I'm now trying to...

In the study mentioned, they were injecting weekly. That means they were injecting a fairly large blob of oil into the subq tissues. Since there is relatively slow absorption from the subq tissues via the lymphatic system and bloodstream, I suspect the residence time for the big blob of oil...

Interesting point. The enanthate contains sesame oil. My new cypionate prescription contains cottonseed oil. I do not know what my old cypionate contained.