Recent content by BigO42

I've had the 3 am wake ups in a panic for no reason regardless. I've believe my anxiety flare ups are usually due to low E2 (or a combination of low e2 and low T) . . . But I certainly don't want to risk exacerbating the anxiety.

Whys that? Yes, anxiety is my concern. . . I tend to have anxiety issues and I really don't want to exacerbate that.

I did awesome on clomid for 4 years. I took 12.5mg once every 3 days. I also mixed a very small dose of anastrozole .08mg every 4th or 5th day. At 4 years I crashed. In hindsight I think it was more to do either anastrole driving down e2, I think I probabaly didn't need it. That frequency...

I am planning to begin a full TRT regimen after 4 years of clomid. Based on my labs and history, defy is recommending T cyp mwf and 250iu hcg t/th/s. I am lower end SHBG when off clomid and usually lower end E2. I'm 37 and have 4 kids and my wife and I have agreed 4 is enough so I'm not super...

I was on clomid for about 4 and a half years. Initially on 15 mg every third day. . . And then after 2 years went to 12.5 ever 3rd day (so I could buy 50mg tabs for cheaper and split them). I took .08mg anastrozole ever 4-5 days. I felt GREAT for 4 years and then CRASHED horribly. My pre...

I did clomid for 4 and a half years. Started at a custom compounded 15 mg once every 3rd day with .08mg anastrozole once every 4-5 days. Felt awesome for a long time and cut clomid to 12.5 Mg evey 4th day about 2 years in and then even every 5th day sometimes. Still felt awesome. Total T...

I would also add that overtraining seems to be a big issue with me. I feel significant issues with fatigue, low mood and sleep when I try to hit like I didn't when I was 20 (37 now). But, we have all these websites, instagrammers and fitness gurus who push huge volume and probabaly aren't...

These are solid considerations. I've never done TRT but did clomid to raise my TT from ranging BTW 350-540 to 600-800. FT was BTW 10-14.5 & then 18-20 respectively. Did great for 4 years. Also did a low dose AI to make sure estradiol didnt get too high. After 4 years of feeling great when I...

Defy advised due to the pro estrogenic sides it's vital with clomid to keep estradiol well controlled. But my estradiol was always low end of mid even with the AI so maybe I'd be okay without it. I'm just thinking as infrequently as I was taking clomid, I'm wondering if mood/ anxiety resulted...

I don't have values at hand but pre clomid my shbg was always on the low end. This is why defy said I was a good clomid candidate. It crept up a little on clomid but never beyond mid range. My theory is that given my extremely low dose of clomid my mood sides were more related to low...

Seeking advice. I am 37 years old. I've been on this journey for 5-6 years after significant chronic fatigue and anxiety symptoms sought to me start doing the thorough medical work up my family doctor refused to do. Prior to any intervention my Total T levels were usually between 390-530 and...

Curious on your on your progress with TRT. I am late 30's but followed a similar path. I was on clomid for 4 (15 mg once every 3-4 days with .08mg anastrzole about once every 5 days) years and felt great, and then had sudden onset anxiety earlier this year (i had anxiety pre clomid). When I...