Recent content by Aki

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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    I'm not sure I totally follow. But just to "think out loud" here: If you mean (with me trying to phrase it in a drastically simplified way) that the body tries to maintain a certain level of free-T (said level being determined by genetics, environment, health, lifestyle, etc. and thus sometimes...
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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    Even if I were inclined to try it, I wouldn't be able to acquire it, unfortunately.
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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    It was recommended to me by the guy who I was taking advice from. I think he gave a reason but I can't recall at the moment. Anyway, initially (as is always the case with me and clomid) I felt good so there didn't seem to be any reason to not go along with it. I also remember reading about a...
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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    50 mg/week taken over two consecutive days. (25 mg first day in the evening, 12.5 mg twice the next day)
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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    @Mastodont I tried taking a very low dose of proviron for a couple of weeks (I think it was one 25 mg pill weekly divided into two doses). Initially I felt some improvement but later on I started feeling what I describe as my low-estrogen symptoms (the main one being my body temperature feels...
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    anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?

    Hi all, Condensed "TL;DR" version of my question: has anyone who has been on clomid to treat secondary hypogonadism tried a low dose of mesterolone (proviron) to reduce the SHBG increase ensuing from using clomid? If so, can you tell me about your experience? Context/long version: I have...
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    searching private conversations?

    Sorry if this has been asked before or covered somewhere else, but is there a way to search for text within one's private conversations, whether all conversations or a particular one?
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    Anyone else obsessed with testosterone?

    I know this thread is a few months old, but this message caught my eye.. Unless I'm very much mistaken, to have a free T level of 93 ng/dL (calculated with an SHBG of 28) requires a total T of about 2800 ng/dL(!) A free T of 200 ng/dL would mean a total testosterone > 5500 ng/dL. I thought...
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    why does exogenous T cause my already low SHBG to plummet further?

    Right, but you would look for a good initial subjective response as well as the lab values of hormones that are indirectly influenced (estrogen, SHBG, etc.), wouldn't you? For example - hypothetically - I might've stuck to my doctor's protocol of sustanon-250 every two weeks for three doses...
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    why does exogenous T cause my already low SHBG to plummet further?

    OK, that SHBG value seems very low. How do you feel at your current dosage?
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    so what *are* the possible causes of late-onset secondary hypogonadism?

    Wow, didn't know this topic would spark such a discussion. I have only glanced through the replies whilst scrolling down, but I feel I owe it to everyone to read their replies with due consideration (which I intend as soon as I have time).
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    why does exogenous T cause my already low SHBG to plummet further?

    Right.. so the main thing seems to be is to try to get a faster-acting testosterone so things can stabilise quicker. I wonder if it would be possible to calculate/estimate what dose to take based on an initial dose that feels "just right"? Like say (for argument's sake) I find that 30mg every...
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    so what *are* the possible causes of late-onset secondary hypogonadism?

    @Gman86 and @Cataceous - appreciate the responses I too have some recollection of the feedback mechanism whereby LH/FSH production is signalled. And if I remember correctly, clomid works by blocking the estrogen receptors, fooling the pituitary into producing more LH and FSH and consequently...
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    so what *are* the possible causes of late-onset secondary hypogonadism?

    I realise I'm asking a very big question, but it seems (barring a pituitary tumor or head trauma) doctors don't seem to have any explanation for late occuring secondary hypogonadism. I even asked the late Dr. Crisler on the phone once, and he couldn't offer any suggestion. Some salient facts...
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    why does exogenous T cause my already low SHBG to plummet further?

    @Cataceous and @Vince Carter thank you both for your insight and experience. Just as I had decided, I didn't taken the second shot sustanon-250 shot, which was due three days ago as per the once shot per two weeks schedule. I am going to the see the endo again and try to see if he can offer me...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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