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I'm not sure I totally follow. But just to "think out loud" here: If you mean (with me trying to phrase it in a drastically simplified way) that the body tries to maintain a certain level of free-T (said level being determined by genetics, environment, health, lifestyle, etc. and thus sometimes...

Even if I were inclined to try it, I wouldn't be able to acquire it, unfortunately.

It was recommended to me by the guy who I was taking advice from. I think he gave a reason but I can't recall at the moment. Anyway, initially (as is always the case with me and clomid) I felt good so there didn't seem to be any reason to not go along with it. I also remember reading about a...

50 mg/week taken over two consecutive days. (25 mg first day in the evening, 12.5 mg twice the next day)

@Mastodont I tried taking a very low dose of proviron for a couple of weeks (I think it was one 25 mg pill weekly divided into two doses). Initially I felt some improvement but later on I started feeling what I describe as my low-estrogen symptoms (the main one being my body temperature feels...

Hi all, Condensed "TL;DR" version of my question: has anyone who has been on clomid to treat secondary hypogonadism tried a low dose of mesterolone (proviron) to reduce the SHBG increase ensuing from using clomid? If so, can you tell me about your experience? Context/long version: I have...

Sorry if this has been asked before or covered somewhere else, but is there a way to search for text within one's private conversations, whether all conversations or a particular one?

I know this thread is a few months old, but this message caught my eye.. Unless I'm very much mistaken, to have a free T level of 93 ng/dL (calculated with an SHBG of 28) requires a total T of about 2800 ng/dL(!) A free T of 200 ng/dL would mean a total testosterone > 5500 ng/dL. I thought...

Right, but you would look for a good initial subjective response as well as the lab values of hormones that are indirectly influenced (estrogen, SHBG, etc.), wouldn't you? For example - hypothetically - I might've stuck to my doctor's protocol of sustanon-250 every two weeks for three doses...

OK, that SHBG value seems very low. How do you feel at your current dosage?

Wow, didn't know this topic would spark such a discussion. I have only glanced through the replies whilst scrolling down, but I feel I owe it to everyone to read their replies with due consideration (which I intend as soon as I have time).

Right.. so the main thing seems to be is to try to get a faster-acting testosterone so things can stabilise quicker. I wonder if it would be possible to calculate/estimate what dose to take based on an initial dose that feels "just right"? Like say (for argument's sake) I find that 30mg every...

@Gman86 and @Cataceous - appreciate the responses I too have some recollection of the feedback mechanism whereby LH/FSH production is signalled. And if I remember correctly, clomid works by blocking the estrogen receptors, fooling the pituitary into producing more LH and FSH and consequently...

I realise I'm asking a very big question, but it seems (barring a pituitary tumor or head trauma) doctors don't seem to have any explanation for late occuring secondary hypogonadism. I even asked the late Dr. Crisler on the phone once, and he couldn't offer any suggestion. Some salient facts...

@Cataceous and @Vince Carter thank you both for your insight and experience. Just as I had decided, I didn't taken the second shot sustanon-250 shot, which was due three days ago as per the once shot per two weeks schedule. I am going to the see the endo again and try to see if he can offer me...

Thanks.. besides injectable testosterone, I can think of oral and gel as alternatives (although again I don't know about their availability). Seems gel might be good (if I remember correctly, Dr. Crisler advocated its use in his Low T book, although I don't have it at hand). Are these good...

@Vince Carter So (assuming I might need to maintain a lower level of estrogen) does that mean that I would probably need an AI? @Cataceous Thanks, I'll ask about the available options regarding esters Thanks.. I'm just trying to make the best of a bad situation (by which I mean the lack of...

Thank you for the quick reply, Vince. Right now I need all the help I can get. My SHBG indeed tends to be that low. In fact, the only time I've recorded my SHBG touching 30 is when I've been on clomid continuously for upto a year (out of the dozen or so times I've had SHBG tested, over the past...

So as I mentioned in another thread, my endo prescribed sustanon-250 once every two weeks, with review after three shots (labs taken day before third shot). I am aware of the T-level fluctuation related issues with high-dose low-frequency injections (half-lives and all that) but my problem isn't...

@DannyManWalesUK thanks, mate. Actually, I had my injection today morning and I have been progressively feeling worse. Even the last time I had used sustanon-250 (many years ago) I do not remember feeling this bad. I don't think I will ever inject the whole sustanon-250 ever again.

Don't mean to hijack the thread, but it seems very relevant to my current situation.. My SHBG has steadily been falling ever since I stopped clomid several months ago (it had peaked at around 30). It was 21 when I had it tested yesterday (although I believe it would eventually have reached...

As I mentioned above, he decided to start me off on one shot every two weeks. And he said he was open to increasing it, by reviewing labs taken before the third shot. And I am getting my hands on the ampules themselves, so if needed I'll just learn how to self-administer if needed. I don't know...

My FT4 tends be borderline low. The last one was 12.4 (reference range: 11.6-21.9), but I have not tested for FT3 or reverse T3. Also, at one point long time ago I was checking my body temperature immediately on waking up, Wilson's test or something (controversial, if I recall correctly). From...

Revised plan: I will get the labs done (testosterone, SHBG, estradiol at least) first before getting the first shot. If my guess is correct, by now my SHBG will have settled down at the mid-teens. I think if this time round I have the same "felt absolutely nothing" experience, I'll suggest to...

Thank you, this "felt absolutely nothing" is consistent with my own first experience with sustanon-250 several years: I felt absolutely nothing. And even though I (later) came to know that low-SHBG men do better with higher frequency shots at lower dose (like you and Cataceous reminded me) I did...

Thanks for the replies, gents. So I had my appointment yesterday and here's the situation so far: the doc is starting me off straightaway on 250 mg every two weeks (instead of every three weeks). He wants me to do a total of three shots, and get labs done the day before the third shot, so if...

Thanks for the reply. The endo did indicate that based on the response he might increase the shot frequency. I don't know how far he'll be willing to go, but then I also don't know what would feel ideal for me. In a sense this discussion is a bit hypothetical because the first time I was put on...

Hi all, ----- I'm cross-posting this (with some alteration) from the All Thing Male forums, where I used to be somewhat more active in the past. I hope that's all right. In the extremely unlikely chance someone has the time or interest to read my history, it's all there on ATM forums. Please...

How (bad?) are these thyroid numbers? FT4 9.9 (ref range 9.0 - 20.0) TSH 1.24 (ref range: 0.45 - 4.50) I believe the units are pmol/L for FT4 and mIU/L for TSH. On previous tests I've had TSH values to be higher (closer to mid-range) but my FT4 has consistently been hovering just above...

Hi all, I was recently prescribed some Celebrex (celecoxib) for persistent lower back pain. I took it for about two week (200 mg/day) and it provided relief for the back pain symptoms. The last dose was 3 nights ago. During the second week while I was on celebrex, my state of mind (mood, mental...

Thank you for weighing in, Dr. Saya. After this, I don't think I'll ever consider trying danazol again. Do you happen to know if danazol negatively affects the lipid profile? My numbers were pretty bad (low HDL, high LDL & cholesterol) when I had labs done shortly after quitting danazol although...