List of high Estradiol symptoms

[lcvl]

We all know that gyno is the most evident/worst manifestation of high E2. But from what I've experienced personally and learned from others on diff forums, gradual increase of E2 in the body can have a wide range of symptoms, from very subtle to more pronounced.

Trying to compile a list here. Feel free to add your own experience.

- No morning wood/spontaneous erections
- Decreased erection quality/ED (not affecting libido that much, in my case)
- Penis hanging differently/less bood flow in its flaccid state/kind of "hollow", less full
- Worse sleep quality
- More frequent urination at night (enlarged prostate?)
- Negative outlook at life (for no apparent reason)
- Anxiety
- Mood swings
- Water retention/puffiness
- Very deep eye circles (related to sleep quality?)
- Sudden surge in acne
- Tiredness/lower energy levels even after 7-9 hours of sleep
- Sensitive nipples

Thanks!

 

[MikeXL]

I didn't know many of these as E symptoms

 

[maxadvance]

Sounds like a list of things that could indicate low E too, just sayin

 

[Nelson Vergel]

- No morning wood/spontaneous erections. MAY BE
- Decreased erection quality/ED (not affecting libido that much, in my case). MAY BE
- Penis hanging differently/less bood flow in its flaccid state/kind of "hollow", less full . NOT REALLY
- Worse sleep quality.NOT REALLY UNLESS YOU HAVE NIGHT SWEATS
- More frequent urination at night (enlarged prostate?) NOT REALLY
- Negative outlook at life (for no apparent reason) NO ONE HAS PROVEN THIS AT ALL
- Anxiety NOT PROVEN
- Mood swings NOT PROVEN
- Water retention/puffiness MAY BE
- Very deep eye circles (related to sleep quality?) NOT AT ALL UNLESS YOU ARE NOT SLEEPING WELL
- Sudden surge in acne NOT AT ALL
- Tiredness/lower energy levels even after 7-9 hours of sleep. NOT AT ALL. SLEEP APNEA?
- Sensitive nipples MAY BE BUT TRT CAN CAUSE THIS. VERY DIFFERENT FROM ENLARGED MAMMARY GLAND.

 

[lcvl]

Eh eh eh... I was kind of expecting this from you, Nelson...

Anyway, of course most of it is just anedoctal evidence, not backed up by any study... Like many other things in the field of TRT, so it seems...

 

[Nutpuncher]

My last 2 e2 was something in the fifties & sixties. Only symptoms that I got is lowered libido and harder to obtain were errection.

 

[Dr. John Crisler]

- No morning wood/spontaneous erections. MAY BE
- Decreased erection quality/ED (not affecting libido that much, in my case). MAY BE
- Penis hanging differently/less bood flow in its flaccid state/kind of "hollow", less full . NOT REALLY
- Worse sleep quality.NOT REALLY UNLESS YOU HAVE NIGHT SWEATS
- More frequent urination at night (enlarged prostate?) NOT REALLY
- Negative outlook at life (for no apparent reason) NO ONE HAS PROVEN THIS AT ALL
- Anxiety NOT PROVEN
- Mood swings NOT PROVEN
- Water retention/puffiness MAY BE
- Very deep eye circles (related to sleep quality?) NOT AT ALL UNLESS YOU ARE NOT SLEEPING WELL
- Sudden surge in acne NOT AT ALL
- Tiredness/lower energy levels even after 7-9 hours of sleep. NOT AT ALL. SLEEP APNEA?
- Sensitive nipples MAY BE BUT TRT CAN CAUSE THIS. VERY DIFFERENT FROM ENLARGED MAMMARY GLAND.

I have seen all the above with high estrogen.

Plus:
DEPRESSION
Lack of Libido
Desire to buy shoes
Subscribing to Redbook Magazine
Watching Oprah

 

[Steelballs]

I am slowly taking my self off of Arimidex because there seems to be no long term proof of what it can be doing to my system. So in this I agree with Nelson. E is important. My E is slowly going up. And I am getting acne now. Not a lot but I normally don't get any. Also my morning wood is not as intense. When my E was lower my wood was so intense it would wake me up. I used to fully blame anxiety and mood swing on E. It does get a little more intense when my E is higher but I attribute my new emotions on TRT which have opened a new window in my life.

 

[Dr. John Crisler]

This whole topic has gone off the rails.

NO ONE advises tanking estrogen.

But E that is too high--for a particular individual--beings water retention, depression, sexual dysfunction, gyno, fatigue and weakness. Also, fat. This nonsense that E burns fat is simply not true. Guys with high E put on fat. I've seen all this thousands of times--literally.

 

[Dr. John Crisler]

I am slowly taking my self off of Arimidex because there seems to be no long term proof of what it can be doing to my system. So in this I agree with Nelson. E is important. My E is slowly going up. And I am getting acne now. Not a lot but I normally don't get any. Also my morning wood is not as intense. When my E was lower my wood was so intense it would wake me up. I used to fully blame anxiety and mood swing on E. It does get a little more intense when my E is higher but I attribute my new emotions on TRT which have opened a new window in my life.

IF your E really was too high, please keep us informed with respect to the changes as it goes back up again.

 

[lcvl]

Really interesting. Thanks everybody for the contributions. Keep them coming!

 

[Dr. John Crisler]

I forgot to mention elevated estrogen also causes BPH (increases stromal proliferation).

And is known to increase the risk of numerous forms of cancer.

 

[Gene Devine]

I forgot to mention elevated estrogen also causes BPH (increases stromal proliferation).

And is known to increase the risk of numerous forms of cancer.

^^^^This.

Why do men over 50 have a significantly higher incidence of Prostate Cancer and men of the age 25 almost none???

Estrogen levels.

 

[Vince Carter]

I get the night sweats, I think that's my first most noticeable appearance of Estrogen, also notice stiff nips, though not sensitive or puffy so I tend to discard that. Beyond that I get moody, can be easier to get angry. Also noticeable with NO stack/supplements and a PDE5 noticeable ED/EQ without much loss of libido, or penile sensitivity.
I've got a test in now, Quest is taking way too long with it...but I think the HCG, I just don't like it and Estrogen is typically why, HCG just makes it harder. Really thinking of cutting from 500iu 2XW to 250iu 2XW, something like that.

 

[Dr. John Crisler]

I get the night sweats, I think that's my first most noticeable appearance of Estrogen, also notice stiff nips, though not sensitive or puffy so I tend to discard that. Beyond that I get moody, can be easier to get angry. Also noticeable with NO stack/supplements and a PDE5 noticeable ED/EQ without much loss of libido, or penile sensitivity.
I've got a test in now, Quest is taking way too long with it...but I think the HCG, I just don't like it and Estrogen is typically why, HCG just makes it harder. Really thinking of cutting from 500iu 2XW to 250iu 2XW, something like that.

Please note the bolded. Yup--estrogen issues. LOL

Seriously, it amazes me when people--especially my colleagues--claim estrogen should not be manipulated. I've literally seen thousands of men have their negative estrogen symptoms dry up with Anastrazole.

 

[midlifealpha]

As recently posted in my Blood Issues my Sensitive Estrodiol was 104.2 with T levels of 999 and Free T of 32.0. Also TSH was out of whack. From my previous TRT doc I had stopped taking Anastrozole so I had quite a build up and figured taking 2-3 per week would not hurt. I also gave up all caffeine as I felt I had Adrenal Fatigue symptoms and my TSH was very high, consistent with Adrenal Fatigue.

Symptoms I have currently
I gained approximately 25 lbs of fat
Extremely irritable, nearly beat up a guy the other day for popping off to me as he was walking and cussing out his girlfriend and I stopped and asked if there was a problem. We exchanged harsh words with me in my car and I followed him into the gas station but he walked away. Turns out he was just released out of 20 months of prison for theft and getting in a fight would be bad for him, but normally I've always been laid back and just ignored idots. Not that most of the time I'm still laid back but there is this quick change to anger when I feel sighted. For instance somebody cuts in line, I say something. Used to be I blew it off.
Others
- General not give a shit about most things
- Probably some depression
- No nipple pain or anything like that, mostly all mental and my wife says I'm like a different person

Please note the bolded. Yup--estrogen issues. LOL

Seriously, it amazes me when people--especially my colleagues--claim estrogen should not be manipulated. I've literally seen thousands of men have their negative estrogen symptoms dry up with Anastrazole.

 

[DxHypo]

Add constipation as a symptom of high estrogen in some people. I just got over at least 2 months of SEVERE constipation as a result of my E2 going up 4 points as a side effect of oral DHEA supplementation. Got my DHEA level up ok but the aromatization and resulting constipation was not worth it.

 

[Dr. John Crisler]

As recently posted in my Blood Issues my Sensitive Estrodiol was 104.2 with T levels of 999 and Free T of 32.0. Also TSH was out of whack. From my previous TRT doc I had stopped taking Anastrozole so I had quite a build up and figured taking 2-3 per week would not hurt. I also gave up all caffeine as I felt I had Adrenal Fatigue symptoms and my TSH was very high, consistent with Adrenal Fatigue.

Symptoms I have currently
I gained approximately 25 lbs of fat
Extremely irritable, nearly beat up a guy the other day for popping off to me as he was walking and cussing out his girlfriend and I stopped and asked if there was a problem. We exchanged harsh words with me in my car and I followed him into the gas station but he walked away. Turns out he was just released out of 20 months of prison for theft and getting in a fight would be bad for him, but normally I've always been laid back and just ignored idots. Not that most of the time I'm still laid back but there is this quick change to anger when I feel sighted. For instance somebody cuts in line, I say something. Used to be I blew it off.
Others
- General not give a shit about most things
- Probably some depression
- No nipple pain or anything like that, mostly all mental and my wife says I'm like a different person

I've only seen E2 that high in alcoholics, due to shunting from Androstenedione.

Don't want to set you off, though! LOL