Injecting at night vs day

fmalianos

Member
I know everyone has their own preference on what time of the day but I was thinking...

If a male's body naturally produces testosterone during sleep, wouldn't it make sense to inject at bedtime to mimic the body's own natural state? I inject around lunch time 3times a week subq.

Any comments, thoughts?
 
Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 😊
 
Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 

no benefit, to daily injecting compared to three days a week
 
no benefit, to daily injecting compared to three days a week

I've read this many times, but when my E2 ran wild this past summer, I went from twice-weekly dosing to three-day-a-week doing. Estradiol dropped a bit, when I went to daily dosing in an effort to avoid an AI, my E2 slid right down into range. I was surprised, but pleased.
 
I've read this many times, but when my E2 ran wild this past summer, I went from twice-weekly dosing to three-day-a-week doing. Estradiol dropped a bit, when I went to daily dosing in an effort to avoid an AI, my E2 slid right down into range. I was surprised, but pleased.
That's good to know, did it affect your testosterone panel in any other ways.
 
Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 

How do you feel on 3 times per week? How did you feel on every day inject? What caused you to switch? I guess im lucky in that I have done inject every 3.5 days with no problems and feel great. I think I would have needle fatigue if I had to inject every day or every other.
 
How do you feel on 3 times per week? How did you feel on every day inject? What caused you to switch? I guess im lucky in that I have done inject every 3.5 days with no problems and feel great. I think I would have needle fatigue if I had to inject every day or every other.

Oddly, I don't have any issues with daily injection. I expected to, fully expected to, but it's a part of my morning routine. But, you're right, had every 3.5 days worked, I'd have been delighted. All in the effort, successful, to manage E2 without an AI.
 
I can understand why one would inject every day to have more control over E to avoid an AI. That's great that you got it figured out CoastWatcher. Seems like its highly individual as far as protocols go and what works for each of us. I guess I was curious if he was having trouble with E or something else that caused him to switch to more frequent injections.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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