Estradiol levels

Ty Nordic

Member
I've been on 100 mg of test cyp for around 2 years. My estrogen/estradiaol levels were crazy-high at first, but anastrozole seemed to calm things down. My testosterone levels are now at 1000, which my Doc says are too high, so we're going down to 80 mg a week. My estradiol levels are at 11.7 (ultrasensitive test). I'm not sure if this number is high, low, or just right... Any advice?
 
I've been on 100 mg of test cyp for around 2 years. My estrogen/estradiaol levels were crazy-high at first, but anastrozole seemed to calm things down. My testosterone levels are now at 1000, which my Doc says are too high, so we're going down to 80 mg a week. My estradiol levels are at 11.7 (ultrasensitive test). I'm not sure if this number is high, low, or just right... Any advice?

I don't understand why your doctor feels a testosterone level of 1000 is "high". You're still in the range that Labcorp publishes for total testosterone. Mine floats in the mid-900/low-1000 range and I feel great. Your estradiol is on the low side - do you even think you need to maintain your anastrozole? Most importantly - how are you feeling? Don't treat numbers, react to your body's subjective response to your therapy.
 
1000 is okay as long as you feel good.

Your E2 is on the low end; better in the low 30's.

What was your Free T, Hematocrit and PSA?
 
I've been on 100 mg of test cyp for around 2 years. My estrogen/estradiaol levels were crazy-high at first, but anastrozole seemed to calm things down. My testosterone levels are now at 1000, which my Doc says are too high, so we're going down to 80 mg a week. My estradiol levels are at 11.7 (ultrasensitive test). I'm not sure if this number is high, low, or just right... Any advice?
Ty, if you can please post a testosterone panel, I would agree your estrogen is too low. Most important, how are you feeling.
 
You need to think about a new doc as well. 1000 is within normal limits and as long as you feel good, is not a level that needs to be lowered. Way too low on E2 as well.
 
Again, the variable that just never gets addressed is Free/Bio Available Test. My Test Serum could be 700ng/dl, yours could be 1,000ng/dl, however, I could very well have higher amounts of active testosterone in my body.

What is the reference range on your E2 Ultra S assay?
 
Thanks for the input on the Anastrozole. I will do the .5 twice a week.
Another concern I have, is my FSH is .3, and my LH is .1. I have no idea what that means, but both are outside "normal" ranges. I am injecting 1000 IU of HCG per week (333 MWF).
 
Thanks for the input on the Anastrozole. I will do the .5 twice a week.
Another concern I have, is my FSH is .3, and my LH is .1. I have no idea what that means, but both are outside "normal" ranges. I am injecting 1000 IU of HCG per week (333 MWF).

I would go further than that... .25mg twice a week, though if you want to cut the dose down in a conservative manner .5mg would be fine. Make small changes, one thing at a time.

LH/FSH while on T will be statistically zero, which is normal. Your Dr testing those two is wasting your money, insurance, blah blah blah
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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