Varicocele Surgery Improves Testosterone and Sexual Function

Nelson Vergel

Urology. 2016 May 16. pii: S0090-4295(16)30194-7. doi: 10.1016/j.urology.2016.04.044. [Epub ahead of print]

Improvements in Patient Reported Sexual Function after Microsurgical Varicocelectomy.
Najari BB1, Introna L2, Paduch DA3.


To evaluate whether varicocelectomy improves both serum testosterone and sexual function, as assessed by the Male Sexual Health Questionnaire (MSHQ).


A retrospective chart review of patients who have undergone varicocelectomy and had both pre- and post-operative MSHQ was performed. The MSHQ is a clinically validated questionnaire that assesses erectile function, ejaculatory function, and sexual satisfaction, with higher scores indicating better function. Clinical parameters pre and post-varicocelectomy were compared with paired t-test.


Thirty-four patients met study criteria. Seventeen patients (50%) presented for infertility, and the remaining 13 had symptomatic varicocele associated with hypogonadism. Average post-surgical follow up was 20.6 ±12.5 months. The majority of men in the study had bilateral varicoceles and left grade III varicoceles. Significant improvements in the total MSHQ score (.3.9 ±8.7, p=0.027), the MSHQ erectile function (1.2 ±2.3, p=0.007), and the MSHQ ejaculatory function (1.4 ±3.1, p=0.018) domains were seen. Fifteen (44%) men saw improvement in their erectile function and 18 (53%) saw improvement in ejaculatory function. The improvement in serum testosterone was also significant (136.0 ±201.3 ng/dL, 0.007).


Microsurgical repair of varicocele not only improves testosterone, but also improves patient reported erectile and ejaculatory function. Patients can confidently be counseled that varicocelectomy has the potential to improve sexual function along with serum testosterone.

Online statistics

Members online
Guests online
Total visitors

Latest posts