Subq Injections Liver Enzymes

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Bishop

New Member
Just curious if any of you have gotten elevated ALT levels from TRT. I've been told high protein diets and hard weight training can cause it as well. I'm trying to figure out a cause.

Mine came back as normal AST but ALT was 65 and normal is 45 I believe in the test I took.

Everything else was pretty much optimal.

Thanks!
 
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Gene Devine

Super Moderator
A ton of things can cause elevated liver enzymes...any things from booze to OTC drugs to training to inflammation.

Testosterone injections bypass the liver so this would not be a contributor.
 
Last edited:

madman

Super Moderator
Just curious if any of you have gotten elevated ALT levels from TRT. I've been told high protein diets and hard weight training can cause it as well. I'm trying to figure out a cause.

Mine came back as normal AST but ALT was 65 and normal is 45 I believe in the test I took.

Everything else was pretty much optimal.

Thanks!


I just recently had full blood work and everything overall was ok except my alanine aminotransferase came back HI 57 RANGE <50 U/L

Nothing I can think of has changed, I lift heavy 3x week, do not drink/smoke/drugs/prescriptions and eat healthy overall lots complex carbs/vegetables/lean protein..............taking in 4000cal/day,500 grams carbs,200 grams protein, just of 100 grams fats roughly mainly from eating 2.2lbs extra lean hormone free beef and adding in some fish oil. Only take creatine/beta-alanine/l-citrulline malate, vitamin d 5000iu,co-q10.

Only think I can think I have changed since my ALT was in range was adding in the 2.2 lbs extra lean beef and the fats and the 100 grams fats I am getting from that are roughly 48%mono/50% saturate.

I just started sub-q trt injections 6 weeks ago but I know that injection does not affect liver enzymes.

I am worried as my family physician called this morning and wants to send me for more testing.
 

madman

Super Moderator
Gene should I be worried that I may have hepatitis or fatty liver? I worked out heavy the night before my blood work but I thought strenuous exercise only affect AST where as ALT is mainly isolated to the liver?
 

Bishop

New Member
From what I have read high protein as well as heavy lifting raises both AST and ALT. There is supposedly another test I think GGT? That supposedly will show normal if the increase is due to diet and training but abnormal if hepatitis or something else is to blame.
 

Gene Devine

Super Moderator
Gene should I be worried that I may have hepatitis or fatty liver? I worked out heavy the night before my blood work but I thought strenuous exercise only affect AST where as ALT is mainly isolated to the liver?

As I said, many things can cause elevated liver enzymes...even heavy training and supplements among a ton of other things...elevated liver panels are pretty common.

Just keep an eye on it on your next labs and see where you are. Slightly elevated liver enzymes are generally nothing to really worry about.
 

isos266

New Member
I can attest to the notion that heavy training before bloodwork raised my AST and ALT. I took a few days off of the gym before my next bloodwork and AST and ALT were normal.
 

Bishop

New Member
Just got back from my appt and doc said the same thing. 65 is not of concern to him. Strangely I continue to have to lower my dose to stay in an acceptable range.

With 80mg every 4 days I was 1200 in the trough.
 
I have not found heavy weights or high protein to have effected my AST or ALT. I would offer this advice though that you should always fast atleast 8 if not 12hrs before having a CBC or CMP test. This can also drive your Creatinine and other kidney markers above range if you're not fasted and pounding on weights or are not fasted.
For instance I lift M-Th, I typically do bloods on Mon first thing so I get 72hrs off from the gym and a good chance to fast overnite before I test.
 
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