i wrote a few articles for Dr. Barrett's Quack Watch beck in the 90's. I have been fighting supplement quackery for a long time. The hard part of this is it is honestly a buyer beware game. You either fall for the hype and waste your money on a hope and a dream or you educate your self and read ever research study that come out about the supplement before you even consider using it. Yea, I have wasted money too. I have seen some recent television adds on Omega 3 that sure fall into the hope and a dream category, I also know enough about Omega 3 that I am not going to give them my money. When you use celebrities to advertise your product I promise you are just ripping people off. I just make it a point to NEVER buy anything I see advertised on TV. I am certainly not familiar with David Sinclair, so I have yet to form an opinion.Yes, this is exactly what I was talking about in the Vitamin D thread. After you have been through enough of these cycles you start build a measure of immunity. Someone brought up David Sinclair on another thread -- don't get me started about him and resveratrol.
The western diet is currently about 16:1, Omega 6 to Omega 3. In fact, The average American now consumes 9% of their energy in the form of omega 6 fats. Toxicity levels begin at 4% We are taking in WAY too much Omega 6 in our diet, a ratio of 4:1 is much healthier. We have pushed very hard since the 70's to stay away from saturated fats and use more vegetable oils. So we take in way too many more inflammatory Omega 6s.So what do you think about omega index? Or omega3/omega6 ratio?
One should not make projections from old mice studies when evaluating supplements.
In a human intervention study, Omega-3 failed to reduce the progression to late age-related macular degeneration (AMD) (hazard ratio close to 1 i.e. no effect), while Lutein/zeaxanthin had a moderate reduction of the risk (hazard ratio 0.91). Supplementing with beta-carotene (believed to also improve eye health) lead to higher rates of lung cancer in smokers:
Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration ProgressionAREDS2 Report 28
That is why, if you search for the current AREDS 2 supplement for eyes, they do NOT contain omega-3. They sell a couple on Amazon and some formulas have an
No wonder people are so confused. Not only are we being given bad information, but it constantly changes. I remember when they said not to use butter, that butter was BAD! That we should instead use margarine. Turns out, butter is way better.The western diet is currently about 16:1, Omega 6 to Omega 3. In fact, The average American now consumes 9% of their energy in the form of omega 6 fats. Toxicity levels begin at 4% We are taking in WAY too much Omega 6 in our diet, a ratio of 4:1 is much healthier. We have pushed very hard since the 70's to stay away from saturated fats and use more vegetable oils. So we take in way too many more inflammatory Omega 6s.
Now, do we necessarily need to take supplements to balance the ratio? Absolutely not, this can be done with changes in the diet. Here is a graphic to show where the push for seed and vegetable based oils started. Carbohydrates also increase at the same time and same rate
View attachment 24529
Here is a decent article on the subject. The only problem I have is the author put in citations but there are no referenced.
People fuss over salt, sugar & cholesterol yet no one talks about PUFA's. PUFA's are often regarded as 'healthy fats'. But when we look at the effect they have on our health & waistline it is clear we have our priorities mixed up. PUFA's are much more damaging than the commonly regarded 'bad' foodswww.alexfergus.com
Yes research constantly changes as we upgrade our knowledge. We know a lot about the functions in the human body, yet know so little. The worst part about the supplement industry is there are a whole lot of scammers out there and the FDA does little to prevent it from happening.
Thats the company that Dr Rhonda Patrick recommended on Joe Rogan podcast. I've been also looking at these tests as they are available in the UK as well.It's worth noting that Omega 6 and 3 "compete" for entry into the cell and an excess of omega 6 will reduce omega 3 by this mechanism. Hence, step one in increasing omega 3 is to reduce omega 6. Any studies that looked at omega 3 supplementation without minimizing omega 6 intake are likely invalid for this reason. There is a company called Omegaquant (no affiliation) that offers fairly inexpensive testing of omega 3 levels.