Can I stop TRT and just switch to HCG+FSH for a few months (and be done w/TRT etc for good) instead of taking SERMS?

Stoak

Member
I am stopping TRT to regain my fertility and I have been to 2 docs (urologist and endo) and both left me with questions. After TRT 1.5 years I had zero swimmers. Wife wants another baby so I decided to stop TRT (also for a couple other reasons - I couldn't fix my chronically low SHBG/hair loss).

My urologist told me to take Clomid for 4 weeks at 50mg ED which is a bit too high IMO... so my plan had been to inject 1000HCG E3dD for 3 weeks since my last inject on Sep 6, and then start Clomid (so last shot, 3 weeks HCG at 1000iu E3D then start clomid at 25mg EOD for 4 weeks). I got a second opinion from and endocrinologist who has actually published papers on testicular failure and she told me to simply "do nothing" and let my body return to homeostasis on its own. My uro asked his partner who is better versed in fertility and his response was "he needs HCG+FSH but a cheaper alternative is Clomid."

The MAIN MAIN MAIN question I have is - can I stop TRT and simply inject HCG+rFSH for a few months, stop and recover my baseline levels of testosterone and endogenous gonadotropin production (assuming it is going to happen) that way instead of taking Clomid? Do we just use Clomid instead of HCG+rFSH for recovery bc it is cheaper? Nobody can seem to answer this for me. Will HCG+rFSH continue to prevent the return to endogenous gonadotropin and testosterone production or will it help?

I have to say the last 3 weeks of HCG at 1000iu E3D while the test cyp has been clearing have been the best my libido has been in years... I'm afraid to lose it w/SERMS. I know my test levels are in the gutter bc I have lost 7 pounds and I'm waking up feeling like I need 10 hours of sleep, but my libido is great for some reason.
 

madman

Super Moderator
I am stopping TRT to regain my fertility and I have been to 2 docs (urologist and endo) and both left me with questions. After TRT 1.5 years I had zero swimmers. Wife wants another baby so I decided to stop TRT (also for a couple other reasons - I couldn't fix my chronically low SHBG/hair loss).

My urologist told me to take Clomid for 4 weeks at 50mg ED which is a bit too high IMO... so my plan had been to inject 1000HCG E3dD for 3 weeks since my last inject on Sep 6, and then start Clomid (so last shot, 3 weeks HCG at 1000iu E3D then start clomid at 25mg EOD for 4 weeks). I got a second opinion from and endocrinologist who has actually published papers on testicular failure and she told me to simply "do nothing" and let my body return to homeostasis on its own. My uro asked his partner who is better versed in fertility and his response was "he needs HCG+FSH but a cheaper alternative is Clomid."

The MAIN MAIN MAIN question I have is - can I stop TRT and simply inject HCG+rFSH for a few months, stop and recover my baseline levels of testosterone and endogenous gonadotropin production (assuming it is going to happen) that way instead of taking Clomid? Do we just use Clomid instead of HCG+rFSH for recovery bc it is cheaper? Nobody can seem to answer this for me. Will HCG+rFSH continue to prevent the return to endogenous gonadotropin and testosterone production or will it help?

I have to say the last 3 weeks of HCG at 1000iu E3D while the test cyp has been clearing have been the best my libido has been in years... I'm afraid to lose it w/SERMS. I know my test levels are in the gutter bc I have lost 7 pounds and I'm waking up feeling like I need 10 hours of sleep, but my libido is great for some reason.

If $$$ is no issue I would just stick with the hCG + rFSH.

Once you stop T levels will return to baseline.




Conclusions

Our results reiterate that FSH in combination with hCG may be considered as an alternative to combination hCG and clomiphene in the treatment of testosterone-induced azoospermia. FSH and hCG dual therapy may result in the more rapid recovery of sperm to the ejaculate being three times faster in the FSH group. Additionally, patients who have failed dual therapy with hCG and clomiphene should be considered for subsequent FSH.
 

JimGainz

Active Member
You can definitely do what you are proposing but you should research restart protocols a little bit more carefully. I think your hCG dose is a little bit high. Maybe try something like 250 to 300 every other day for a few weeks, then add the Clomid at the dose you mentioned above: 25 mg every other day – or 12.5 every day for 4 weeks
 

Jay Ara

Member
I did exactly like that.
stopped TRT, added FSH first and then later HCG.
my protocol was FSH 300 iu eod, HCG 1500 eod.
I went from 0 to 70million in 5 months.
worked for me, no significant side effects, I was much better than natural, no pct, etc…
good luck
Jay
 

Stoak

Member
I had my labwork done... LH and FSH.

LH - .9
FSH 2.8

My Estradiol came back <19pg/mL - it doesn't seem his lab is very sensitive and I think there is still a testosterone test coming (I may be wrong).

This was 31 days since my last injection of 80mg test cyp and 14 days since my last HCG 1000iu inject. I should have started Clomid 2 weeks ago, but delayed bc I wasn't sure what I was doing for the recovery. I finally spoke to a 2nd urologist and he said HCG+rhFSH would keep my natural ability to make gonadotropins shut down. He advised my best path forward if I didn't want to stay on medication for as long as it takes to conceive again is Clomid for 4 weeks 25mg EOD. So I started the Clomid yesterday and have follow up in a month.

Seems at this point 2.8 FSH seems like a good sign and maybe my LH is really low bc I continued HCG until 2 weeks ago. I may not need bazooka drugs to get things going again from a fertility perspective.
 

Stoak

Member
How do you feel?

Everything hurts. I've lost 12 pounds from 2020 to 190. My penis still works but my sex drive isn't really there (I've continued taking 5mg of Cialis which I always have taken dailu for over a year). I'm sleeping fine... I am still making it to the gym but I'm getting a bit weaker. The one thing I have noticed mostly is I'm tired when I wake up and I have a job that requires 30k steps per day. My feet are killing me. They didn't hurt before.
 

Jay Ara

Member
I understand, I have been there myself.

Don’t forget that is for a bigger reason!

Stay strong and good luck on your journey!

All the best to you!
 

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