Update to my e2 (AI) experiment

Weasel

Member
As a follow up to this thread
https://www.excelmale.com/forum/showthread.php?8902-E2-Labs&p=56017#post56017

I've got some one data on my personal experiment with AI and how it affects my e2.

e2: 48.6 (10-42) Protocol was: 140mg test Cyp weekly in EOD dosing, 250iu HCG 3.5d, NO AI

e2: 48.7 (10-42) Same as above minus HCG. This shows that HCG does not increase E2 in my case.

e2:19.8 (10-42) 140mg test Cyp EOD dosing. No HCG and .125mg Anastrozole every 3.5 days

e2 24.7 (10-42) 140mg test cyp EOD dosing. hcg 125iu EOD .0625 anastrozole 3.5d



I find it very interesting how much AI a lot of guys around here use when these minuscule amounts cut mine in half or more. I know we are all different though.

I will be discussing all of these results with our good Dr Saya here in a few days.
 
Yes, AI's are very powerful antagonists in men and most on TRT doses simply don't need it.

BTW, are you really prescribed 140 mg every other day?

What's your total and free testosterone levels like?
 
As a follow up to this thread
https://www.excelmale.com/forum/showthread.php?8902-E2-Labs&p=56017#post56017

I've got some one data on my personal experiment with AI and how it affects my e2.

e2: 48.6 (10-42) Protocol was: 140mg test Cyp weekly in EOD dosing, 250iu HCG 3.5d, NO AI

e2: 48.7 (10-42) Same as above minus HCG. This shows that HCG does not increase E2 in my case.

e2:19.8 (10-42) 140mg test Cyp EOD dosing. No HCG and .125mg Anastrozole every 3.5 days

e2 24.7 (10-42) 140mg test cyp EOD dosing. hcg 125iu EOD .0625 anastrozole 3.5d



I find it very interesting how much AI a lot of guys around here use when these minuscule amounts cut mine in half or more. I know we are all different though.

I will be discussing all of these results with our good Dr Saya here in a few days.

How do you feel now?

24 isn't too bad, assuming it's trough. Not too low or too high.
 
I made the obvious assumption that 140 is being divided accordingly.


Yes 140mg per week, divided into EOD dosing (40mg per)

[TABLE="class: pw0_118 contextfreetbl wrap"]
[TR]
[TD="class: pw0_128"]Tota T 812 (
[/TD]
[TD="class: pw0_128"]300-1080 ng/dL)[/TD]
[/TR]
[/TABLE]
[TABLE="class: pw0_118 contextfreetbl wrap"]
[TR]
[TD="class: pw0_128"]Free T [/TD]
[TD="class: pw0_128"]180 pg/mL
CommentIcon.png

[/TD]
[TD="class: pw0_128"](47-244 pg/mL)[/TD]
[/TR]
[/TABLE]
 
Do you feel any different when using an AI.

I honestly notice very little difference between the different AI doses that I've tried. I do seem to feel a sweet spot for about 2 days after I stop an AI dose. Maybe e2 at 30-35ish would be my sweet spot. But to get there I would need such a small dose of AI that it may not be possible to break it down that far.
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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