Testosterone to Estrodiol Ratio

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ta406

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I've been on TRT for a couple of years now. I'm 5'9, 185lbs and fairly lean. I eat pretty clean for the most part. My protocol is 50mg Test c Monday night and Friday morning. 300iu Hcg with my test injection plus Wednesday night. No AI. My latest blood test showed my TT was 973 and E2 was 30. This is the standard Labcorp E2 test. I have keep copies of all of my labs since starting TRT and I have noticed that my E2 is always low. My current ratio is 32. Looking back on all of my labs, my ratio is typically like this or even higher. I have low libido and ED issues and take 10mg of Cialis EOD. The cialis works well and I also plan on starting Gene's nitric oxide stack soon. I also have anxiety, tired all the time but sleep poorly at night, have a hard time retaining water (thirtsty all the time). I'm wondering if low E2 is to blame. I know this is the opposite problem of most guys. Is there any way to raise my E2? I was thinking about raising my HCG dose? Any help would be appreciated.

I donate blood from time to time. With my TT levels in this range my hematocrit stays within a safe range. I have ran my TT up to 1400 and did have to donate blood as a result. At that time, I was experimenting with a different protocol and was taking .25 mg adex and my E2 was 10. Needless to say that protocol didn't work for me.
 
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I had blood drawn last week as part of my routine checkup and thyroid was one of the tests. I should be getting the results soon. I realize that these are old labs and probably wont help much but about a year ago I had my thyroid and prolactin levels check. I feel the same now as I did then. Here were the results.

Prolactin 9.4 ng/ml 4.0 - 15.2
TSH 1.800 uIU/ml 0.450 - 4.500
Free T4 1.17 ng/dl 0.82 - 1.77
Free T3 2.6 pg/ml 2.0 - 4.4
 
I've been on TRT for a couple of years now. I'm 5'9, 185lbs and fairly lean. I eat pretty clean for the most part. My protocol is 50mg Test c Monday night and Friday morning. 300iu Hcg with my test injection plus Wednesday night. No AI. My latest blood test showed my TT was 973 and E2 was 30. This is the standard Labcorp E2 test. I have keep copies of all of my labs since starting TRT and I have noticed that my E2 is always low. My current ratio is 32. Looking back on all of my labs, my ratio is typically like this or even higher. I have low libido and ED issues and take 10mg of Cialis EOD. The cialis works well and I also plan on starting Gene's nitric oxide stack soon. I also have anxiety, tired all the time but sleep poorly at night, have a hard time retaining water (thirtsty all the time). I'm wondering if low E2 is to blame. I know this is the opposite problem of most guys. Is there any way to raise my E2? I was thinking about raising my HCG dose? Any help would be appreciated.

I donate blood from time to time. With my TT levels in this range my hematocrit stays within a safe range. I have ran my TT up to 1400 and did have to donate blood as a result. At that time, I was experimenting with a different protocol and was taking .25 mg adex and my E2 was 10. Needless to say that protocol didn't work for me.

Since your E2 of 30 was from the standard test, not the ultra sensitive test, you may well have low E2. Rather than guess though, I would go get the ultra sensitive E2 test to see where you really are. You may also have thyroid or cortisol issues going on if you have not tested for them already.
 
Just received my lab results from Labcorp. I have a follow up appointment with the doc in a couple of weeks but I know almost nothing about the thyroid, but I am trying to learn. Could you guys let me know what to make of the results. Again, my symptoms are low libido and ED issues. I also have anxiety, tired all the time but sleep poorly at night, have a hard time retaining water (thirtsty all the time), weakness and fatigue. Thanks in advance


TT 879 348 - 1197
FT 16.7 6.8 - 21.5
E2 20.8 7.6 - 42.6
Free T4 1.28 .82 - 1.77
TSH 1.120 .450 - 4.500
Free T3 2.9 2.0 - 4.4
 
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