Injecting once or twice a week is really dependent upon a few things:
1. If you just don't like injecting yourself than once a week will be better then twice a week.
2. If you have mid to high levels of SHBG once a week will help to lower SHBG levels freeing up more Free Testosterone which is a very good thing.
3. If you have low SHBG and higher E2 levels, twice a week is a much better protocol as it allows for a bit higher SHBG and doesn't provide for higher peaks and lower lows of Testosterone levels - think more stable levels week over week - and this is much more healthier for many men. I stopped using an AI on twice weekly injections!
There you have it.
What injection meds do you use and what dosages? Curious.