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My protocol up until a week ago was 200 mg test cyp IM every 2 weeks (started by the last urologist I went to). I had previously experimented with SQ injections based on the forums and work of Crisler, but probably did not allow long enough for it to stabilize and impatiently switched back to IM every 2 weeks when I did not feel improvement. At 330 lbs I have too much body fat although I have plenty of muscle. Probably 40% BF level for many reasons other than hormones (depression, lack of consistent, exercise, caretaking of my mother who has chronic health issues which require me to be home-bound along with her, etc.)  I have excess fluid retention as well as joint issues, along with some peripheral vascular problems in my legs ( I apparently blew out the valves in my leg blood vessels from heavy weights and the valsalva technique) so I have phlebitis).  Also carrying the classic buddha belly syndrome.  At one point a few years ago I my E2 was at 29 and it's around that number that I felt pretty decent.