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The zuclomiphene isomer of Clomid is estrogenic and is unaffected by AI use. In addition, the excess LH caused by Clomid probably increases intratesticular aromatization, which is a source of estradiol that is more resistant to AIs. A lower dose can certainly help, but it does seem as though relatively few men achieve good long-term results with Clomid. Also keep in mind that zuclomiphene has an extremely long half-life, on the order of weeks, so a lot of patience is required when making adjustments.