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Would like to revive this thread. I am back on Xyosted. In general, it works very well. Somehow, it is more tolerable for me than other forms of enanthate. However, I find that I feel great on the first half of the week and by day six and seven, I run out of gas. Also, I’ve had a flare of acne, likely related to the high levels on the front end of the week.


I am wondering if anyone else can share their experience? It would be great if Xyosted had twice weekly dosing options, but currently, their dosing is fairly rigid. Supposedly, blood levels become stable over time, though. Maybe I need to give it more time to allow levels to stabilize. Been on the current 100mg/week protocol for four weeks.


Would like to hear if anyone else has had similar experiences?


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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