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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Xyosted Dose
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<blockquote data-quote="Cataceous" data-source="post: 249681" data-attributes="member: 38109"><p>It's important to see what your free testosterone is doing. Do you know what your SHBG is like? If it's on the low side then you can still have good free testosterone when total is 500 ng/dL. Ideally you would also test with an accurate method, such as equilibrium dialysis. Another consideration is the half-life of Xyosted. In clinical trials the average was about 10 days, which means with weekly injections the variation in serum testosterone is not excessive. However, this doesn't preclude the possibility of some men being faster absorbers—who would see higher peaks and lower troughs. I'm assuming your current measurement is at trough? You might try to get a peak measurement to see how much higher it is. If it's high enough to push free testosterone out of the physiological range then you may want to rethink the protocol.</p><p></p><p>There are a lot of reasons for not feeling great. Do you have specific indications that they are tied to testosterone? That 100 mg of testosterone enanthate per week is giving you an average of over 10 mg of testosterone per day. The range of natural production is about 3-9 mg per day, with 6-7 mg considered typical for young men. This makes it less likely that you're still suffering from a deficiency, unless it's related to the delivery pattern.</p><p></p><p>That said, some guys have reported increasing the dose frequency of Xyosted to attain higher levels. If I'm remembering correctly, one of them may have been injecting 100 mg every five days. I don't recall anything being said about insurance coverage.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 249681, member: 38109"] It's important to see what your free testosterone is doing. Do you know what your SHBG is like? If it's on the low side then you can still have good free testosterone when total is 500 ng/dL. Ideally you would also test with an accurate method, such as equilibrium dialysis. Another consideration is the half-life of Xyosted. In clinical trials the average was about 10 days, which means with weekly injections the variation in serum testosterone is not excessive. However, this doesn't preclude the possibility of some men being faster absorbers—who would see higher peaks and lower troughs. I'm assuming your current measurement is at trough? You might try to get a peak measurement to see how much higher it is. If it's high enough to push free testosterone out of the physiological range then you may want to rethink the protocol. There are a lot of reasons for not feeling great. Do you have specific indications that they are tied to testosterone? That 100 mg of testosterone enanthate per week is giving you an average of over 10 mg of testosterone per day. The range of natural production is about 3-9 mg per day, with 6-7 mg considered typical for young men. This makes it less likely that you're still suffering from a deficiency, unless it's related to the delivery pattern. That said, some guys have reported increasing the dose frequency of Xyosted to attain higher levels. If I'm remembering correctly, one of them may have been injecting 100 mg every five days. I don't recall anything being said about insurance coverage. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Xyosted Dose
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