Good that she is on BHRT!! I can almost assure you her thyroid numbers wouldn't be that good without the progesterone therapy, thus keeping estrogen dominance in check. Iron serum is usually a factor that tends to be on the low end during peri/post menopausal stages. If the DHEA is naturally staying high, YES, check the adrenals, see if there's anything out of range on cortisol, and the demand it places upstream on pregnenolone, which higher DHEA levels can "sometimes" be a marker for an imbalance.