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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Why do so many Quit TRT?
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<blockquote data-quote="BigTex" data-source="post: 268290" data-attributes="member: 43589"><p>One of the problems I see is all of the cookie cutter formulas running among our TRT clinics. Everyone is put on the same dose combined with an AI whether you need it or not. Here is where the law of individuality comes into play, matching the right patient with the right drug formulation is so important to ensure patient satisfaction and compliance which is essential for maintaining long-term compliance.</p><p></p><p>Most guys hear all of these advertisements about TRT and fall for the "magic bullet." Taking any long term medication is difficult for most. Having to do IM injections once or more a week for the rest of your life is a difficult concept for most. Combine that with expecting TRT is going to solve all of your problems, its just not worth it to many.</p><p></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/24909541/[/URL]</p><p></p><p style="margin-left: 20px"><strong>Results: </strong>The patient characteristics were similar for patients who received topical TRT or short-lasting TRT injections. Of the patients who discontinued therapy during the follow-up period, <strong>the percentages of patients who were still on therapy after 3 months were 52% and 31% for topical TRT and short-lasting TRT users</strong>, respectively. <strong>For cyclic users, t</strong>here was an attrition rate of approximately 40% to 50% of patients in each cycle. For both topical TRT and short-lasting TRT injections, the gap between stopping and restarting therapy tended to decrease over time.</p> <p style="margin-left: 20px"></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/20104673/[/URL]</p><p></p><p style="margin-left: 20px"><strong>Conclusion: </strong>Approximately two-thirds of men with TD who begin TTh will experience symptomatic benefit and will complete at least 12 months of treatment. Benefit was noted in a majority by 3 months.</p> <p style="margin-left: 20px"></p><p>Seems since some of the TU pills have some around, the retention rates have risen as it is much easier to take a pill as opposed to doing injections or using creams. Is this any different from any other long term medication? NO.....<strong>nonadherence can account for up to 50% of treatment failures, around 125,000 deaths, and up to 25% of hospitalizations each year in the United States.</strong></p><p></p><p>[URL unfurl="true"]https://www.uspharmacist.com/article/medication-adherence-the-elephant-in-the-room#:~:text=Nonadherence%20can%20account%20for%20up,chronic%20medications%20is%20around%2050%25.[/URL]</p></blockquote><p></p>
[QUOTE="BigTex, post: 268290, member: 43589"] One of the problems I see is all of the cookie cutter formulas running among our TRT clinics. Everyone is put on the same dose combined with an AI whether you need it or not. Here is where the law of individuality comes into play, matching the right patient with the right drug formulation is so important to ensure patient satisfaction and compliance which is essential for maintaining long-term compliance. Most guys hear all of these advertisements about TRT and fall for the "magic bullet." Taking any long term medication is difficult for most. Having to do IM injections once or more a week for the rest of your life is a difficult concept for most. Combine that with expecting TRT is going to solve all of your problems, its just not worth it to many. [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/24909541/[/URL] [INDENT][B]Results: [/B]The patient characteristics were similar for patients who received topical TRT or short-lasting TRT injections. Of the patients who discontinued therapy during the follow-up period, [B]the percentages of patients who were still on therapy after 3 months were 52% and 31% for topical TRT and short-lasting TRT users[/B], respectively. [B]For cyclic users, t[/B]here was an attrition rate of approximately 40% to 50% of patients in each cycle. For both topical TRT and short-lasting TRT injections, the gap between stopping and restarting therapy tended to decrease over time.[/INDENT] [INDENT][/INDENT] [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/20104673/[/URL] [INDENT][B]Conclusion: [/B]Approximately two-thirds of men with TD who begin TTh will experience symptomatic benefit and will complete at least 12 months of treatment. Benefit was noted in a majority by 3 months.[/INDENT] [INDENT][/INDENT] Seems since some of the TU pills have some around, the retention rates have risen as it is much easier to take a pill as opposed to doing injections or using creams. Is this any different from any other long term medication? NO.....[B]nonadherence can account for up to 50% of treatment failures, around 125,000 deaths, and up to 25% of hospitalizations each year in the United States.[/B] [URL unfurl="true"]https://www.uspharmacist.com/article/medication-adherence-the-elephant-in-the-room#:~:text=Nonadherence%20can%20account%20for%20up,chronic%20medications%20is%20around%2050%25.[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Why do so many Quit TRT?
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