I experienced the same thing on injections, changing the dosage brought about a weeks worth of libido and erectile improvements, then it all disappeared.

This also happens in men who have abused steroids, and if still having these issues, there doesn’t seem to be a fix, at least in the near future.

Also remember, some EDC’s do block hormones at the receptors.

I theorize this positive response to changing hormones and improvements in libido  and erectile function has to do with over-stimulation. These relatively short acting esters elevate hormones longer and more consistently, unlike natty men.

For years I had treatment failure on injections (cypionate/enanthate), and didn’t absorb T gel and T cream. I finally found something that allows me to have my cake and eat it too!

Jatenzo is very different from cypionate, with a half-life of 6 hours instead of 5-7 days. On Jatenzo, hormones peak in 2 hours, reaching midpoint at 6 hours and trough at 12 hours. This hormonal rise and rapid decline is why I believe it works so well for me.

No more feeling of over-stimulated, like on injections.