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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Why All Men Should be Tested with the Sensitive Estradiol Test
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<blockquote data-quote="Nelson Vergel" data-source="post: 3905" data-attributes="member: 3"><p>Keith will be writing a post on his experience soon. He used the two methods on the same blood sample.</p><p></p><p>Regular estradiol test result: 95 pg/ml</p><p></p><p>Ultrasensitive estradiol test result: 9 pg/ml</p><p></p><p></p><p>Regular was 10 times the value obtained from ultrasensitive.</p><p></p><p><a href="https://www.excelmale.com/forum/threads/the-sensitive-e2-test-an-unambiguous-endorsement.12742/" target="_blank">The Sensitive E2 Test - An Unambiguous Endorsement</a></p><p></p><p><a href="https://www.discountedlabs.com/blog/post/why_men_should_be_tested_using" target="_blank">Sensitive Estradiol Blood Test: The Only Accurate Assay for Men</a></p><p></p><p></p><p><strong>Thread: <a href="https://www.excelmale.com/forum/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management" target="_blank">Role of Estradiol in Men and Its Management</a></strong></p><p></p><p>I was able to find the right estradiol blood test based on mass spectrometry/liquid chromatography:</p><p></p><p><a href="https://www.discountedlabs.com/estradiol-sensitive-lc-ms-ms" target="_blank">Affordable sensitive estradiol test</a></p><p></p><p></p><p><span style="font-size: 18px"><strong>Study: Comparison of total estradiol measured by immunoassay and LC-MS/MS (sensitive)</strong></span></p><p></p><p>Of the subjects, 60 men had total estradiol measured by both the assays. The mean and median total estradiol concentrations measured by immunoassay were 3.95 ± 1.31 and 3.9 [3.1–4.8] ng/dL, respectively. <strong>In contrast, the mean and median total estradiol concentrations measured by LC-MS/MS were lower by almost half </strong>(2.16 ± 1.66 and 1.9 [0.8–3.2] ng/dL, respectively; <em>P</em> < 0.001 for comparison with immunoassay). The total estradiol concentrations measured by the two assays correlated only weakly (<em>r</em> = 0.37, <em>P</em> = 0.004).</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142021/" target="_blank">Reference</a></p><p></p><p></p><p>This is an interesting comparison between the regular and sensitive E2 tests:</p><p></p><p><a href="https://www.excelmale.com/forum/threads/eclia-vs-lc-ms-deviation.19855/" target="_blank">Difference between ECLIA (Regular) vs LC/MS (Sensitive) Estradiol Test Methods</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 3905, member: 3"] Keith will be writing a post on his experience soon. He used the two methods on the same blood sample. Regular estradiol test result: 95 pg/ml Ultrasensitive estradiol test result: 9 pg/ml Regular was 10 times the value obtained from ultrasensitive. [URL='https://www.excelmale.com/forum/threads/the-sensitive-e2-test-an-unambiguous-endorsement.12742/']The Sensitive E2 Test - An Unambiguous Endorsement[/URL] [URL='https://www.discountedlabs.com/blog/post/why_men_should_be_tested_using']Sensitive Estradiol Blood Test: The Only Accurate Assay for Men[/URL] [B]Thread: [URL='https://www.excelmale.com/forum/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management']Role of Estradiol in Men and Its Management[/URL][/B] I was able to find the right estradiol blood test based on mass spectrometry/liquid chromatography: [URL='https://www.discountedlabs.com/estradiol-sensitive-lc-ms-ms']Affordable sensitive estradiol test[/URL] [SIZE=18px][B]Study: Comparison of total estradiol measured by immunoassay and LC-MS/MS (sensitive)[/B][/SIZE] Of the subjects, 60 men had total estradiol measured by both the assays. The mean and median total estradiol concentrations measured by immunoassay were 3.95 ± 1.31 and 3.9 [3.1–4.8] ng/dL, respectively. [B]In contrast, the mean and median total estradiol concentrations measured by LC-MS/MS were lower by almost half [/B](2.16 ± 1.66 and 1.9 [0.8–3.2] ng/dL, respectively; [I]P[/I] < 0.001 for comparison with immunoassay). The total estradiol concentrations measured by the two assays correlated only weakly ([I]r[/I] = 0.37, [I]P[/I] = 0.004). [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142021/']Reference[/URL] This is an interesting comparison between the regular and sensitive E2 tests: [URL="https://www.excelmale.com/forum/threads/eclia-vs-lc-ms-deviation.19855/"]Difference between ECLIA (Regular) vs LC/MS (Sensitive) Estradiol Test Methods[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Why All Men Should be Tested with the Sensitive Estradiol Test
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