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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Why All Men Should be Tested with the Sensitive Estradiol Test
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<blockquote data-quote="Nelson Vergel" data-source="post: 121611" data-attributes="member: 3"><p>Finally, a study comparing the regular versus sensitive estradiol tests.</p><p></p><p><strong>Study: Comparison of total estradiol measured by immunoassay and LC-MS/MS (sensitive)</strong></p><p></p><p>Of the subjects, 60 men had total estradiol measured by both the assays. The mean and median total estradiol concentrations measured by immunoassay were 3.95 ± 1.31 and 3.9 [3.1–4.8] ng/dL, respectively. <strong>In contrast, the mean and median total estradiol concentrations measured by LC-MS/MS were lower by almost half </strong>(2.16 ± 1.66 and 1.9 [0.8–3.2] ng/dL, respectively; <em>P</em> < 0.001 for comparison with immunoassay). The total estradiol concentrations measured by the two assays correlated only weakly (<em>r</em> = 0.37, <em>P</em> = 0.004).</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142021/" target="_blank">Reference</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 121611, member: 3"] Finally, a study comparing the regular versus sensitive estradiol tests. [B]Study: Comparison of total estradiol measured by immunoassay and LC-MS/MS (sensitive)[/B] Of the subjects, 60 men had total estradiol measured by both the assays. The mean and median total estradiol concentrations measured by immunoassay were 3.95 ± 1.31 and 3.9 [3.1–4.8] ng/dL, respectively. [B]In contrast, the mean and median total estradiol concentrations measured by LC-MS/MS were lower by almost half [/B](2.16 ± 1.66 and 1.9 [0.8–3.2] ng/dL, respectively; [I]P[/I] < 0.001 for comparison with immunoassay). The total estradiol concentrations measured by the two assays correlated only weakly ([I]r[/I] = 0.37, [I]P[/I] = 0.004). [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142021/']Reference[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Why All Men Should be Tested with the Sensitive Estradiol Test
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