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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who's currently on T propionate?
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<blockquote data-quote="Cataceous" data-source="post: 167439" data-attributes="member: 38109"><p><em>Low SHBG guys have higher free/unbound testosterone than their converse counterparts. Low SHBG guys would have higher clearance rates than high SHBG guys due to the fact that the amount of free/unbound T is higher at any given time that a high SHBG guy.</em></p><p></p><p><strong>Only when total testosterone is forced to be the same.</strong></p><p></p><p><em>Thus, with higher amount of free/unbound T, low SHBG guys will have a larger amount of readily excretable testosterone given its unbound state, and will subsequently 'run through' a single dosage of T faster than their converse counterparts.</em></p><p></p><p>You seem to be appealing to intuition, which doesn't work in this case. The point you keep ignoring is that with constant testosterone production or absorption the total level of testosterone is not the same for different SHBG and the same underlying metabolism. Total testosterone adjusts to maintain free testosterone, which must be constant for a constant input rate.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 167439, member: 38109"] [I]Low SHBG guys have higher free/unbound testosterone than their converse counterparts. Low SHBG guys would have higher clearance rates than high SHBG guys due to the fact that the amount of free/unbound T is higher at any given time that a high SHBG guy.[/I] [B]Only when total testosterone is forced to be the same.[/B] [I]Thus, with higher amount of free/unbound T, low SHBG guys will have a larger amount of readily excretable testosterone given its unbound state, and will subsequently 'run through' a single dosage of T faster than their converse counterparts.[/I] You seem to be appealing to intuition, which doesn't work in this case. The point you keep ignoring is that with constant testosterone production or absorption the total level of testosterone is not the same for different SHBG and the same underlying metabolism. Total testosterone adjusts to maintain free testosterone, which must be constant for a constant input rate. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who's currently on T propionate?
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