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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who's currently on T propionate?
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<blockquote data-quote="Cataceous" data-source="post: 162914" data-attributes="member: 38109"><p>See the explanation above. In case it's not clear, each person must take measurements to establish his own dose-response parameters. These measurements must be taken when serum testosterone is hardly varying, which means with relatively frequent injections of longer esters. I'd expect the dose-response parameters to be fairly linear, as mine were, but obviously we all have different metabolisms, so the slopes may vary quite a lot between individuals. Here are mine:</p><p>[ATTACH=full]8621[/ATTACH]</p><p>There's also the possibility that these numbers change over time, though mine seem to have been pretty steady over a period of years.</p><p></p><p>This means that my predicted average free testosterone is about 0.6274 times my weekly dose of testosterone. Here's how it fits in with the rest: Suppose I'm injecting 9 mg T propionate a day. This translates to 53 mg testosterone per week. I multiply this by 0.6274 to get a predicted average free testosterone of 33 ng/dL. Now suppose I measure total testosterone at trough of 540 ng/dL and SHBG of 27. I go to the <a href="https://tru-t.org" target="_blank">Tru-T site</a> and find what total testosterone value corresponds to the free T value of 33 ng/dL. I find this to be about 910 ng/dL. Now I know that my trough measurement is 41% under the predicted average, and the predicted peak is 41% over, about 1,280 ng/dL.</p><p></p><p>Though the numbers may be rough estimates, the important point here is that a 40% variation around average serum testosterone is unnaturally large, potentially making the protocol undesirable.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 162914, member: 38109"] See the explanation above. In case it's not clear, each person must take measurements to establish his own dose-response parameters. These measurements must be taken when serum testosterone is hardly varying, which means with relatively frequent injections of longer esters. I'd expect the dose-response parameters to be fairly linear, as mine were, but obviously we all have different metabolisms, so the slopes may vary quite a lot between individuals. Here are mine: [ATTACH=full]8621[/ATTACH] There's also the possibility that these numbers change over time, though mine seem to have been pretty steady over a period of years. This means that my predicted average free testosterone is about 0.6274 times my weekly dose of testosterone. Here's how it fits in with the rest: Suppose I'm injecting 9 mg T propionate a day. This translates to 53 mg testosterone per week. I multiply this by 0.6274 to get a predicted average free testosterone of 33 ng/dL. Now suppose I measure total testosterone at trough of 540 ng/dL and SHBG of 27. I go to the [URL='https://tru-t.org']Tru-T site[/URL] and find what total testosterone value corresponds to the free T value of 33 ng/dL. I find this to be about 910 ng/dL. Now I know that my trough measurement is 41% under the predicted average, and the predicted peak is 41% over, about 1,280 ng/dL. Though the numbers may be rough estimates, the important point here is that a 40% variation around average serum testosterone is unnaturally large, potentially making the protocol undesirable. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who's currently on T propionate?
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