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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who feels better on e5d or e7d compared.to more frequent shots?
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<blockquote data-quote="Cataceous" data-source="post: 209286" data-attributes="member: 38109"><p>You need a <a href="https://www.excelmale.com/forum/threads/tips-on-how-to-blend-propionate-with-enanthate-or-cypionate.23485/" target="_blank">propionate blend</a> for this. Injected daily it can provide a better imitation of the normal diurnal variation in levels.</p><p></p><p style="margin-left: 20px"><em>I'm hopeful that this approach will really shine in cases where guys cannot find a workable TRT dose with steady serum testosterone. For example, there could be side effects at higher levels and a loss of benefits at lower levels and no sweet spot in between. The hypothesis here is that some of the benefits of testosterone are a function of daily peak levels, while problems from excess are more related to average or trough levels. This appears to be the principle behind Natesto. Men taking it are hypogonadal at their baseline testosterone levels, but the significant testosterone peaks provided by the nasal gel are sufficient to relieve the symptoms.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>With a propionate blend one can use 20% less testosterone than with a longer ester and still have the daily peak in serum testosterone match the steady levels of the higher dose. At the same time you've introduced diurnal variation in levels, mimicking what's seen in normal men.</em></p></blockquote><p></p>
[QUOTE="Cataceous, post: 209286, member: 38109"] You need a [URL='https://www.excelmale.com/forum/threads/tips-on-how-to-blend-propionate-with-enanthate-or-cypionate.23485/']propionate blend[/URL] for this. Injected daily it can provide a better imitation of the normal diurnal variation in levels. [INDENT][I]I'm hopeful that this approach will really shine in cases where guys cannot find a workable TRT dose with steady serum testosterone. For example, there could be side effects at higher levels and a loss of benefits at lower levels and no sweet spot in between. The hypothesis here is that some of the benefits of testosterone are a function of daily peak levels, while problems from excess are more related to average or trough levels. This appears to be the principle behind Natesto. Men taking it are hypogonadal at their baseline testosterone levels, but the significant testosterone peaks provided by the nasal gel are sufficient to relieve the symptoms.[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]With a propionate blend one can use 20% less testosterone than with a longer ester and still have the daily peak in serum testosterone match the steady levels of the higher dose. At the same time you've introduced diurnal variation in levels, mimicking what's seen in normal men.[/I][/INDENT] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who feels better on e5d or e7d compared.to more frequent shots?
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