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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who feels better on e5d or e7d compared.to more frequent shots?
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<blockquote data-quote="Cataceous" data-source="post: 209169" data-attributes="member: 38109"><p>I'm probably one to criticize high levels even more than [USER=13851]@madman[/USER]. Here are some of my objections:</p><p></p><p>• Not always, but frequently, there's no attempt to give physiological levels a chance. The low-and-slow approach is ignored and guys start TRT with trough serum free/total testosterone that's near or over top-of-range. Typically this leads to peak levels that are considerably above normal physiology. Many guys end up regretting that they didn't start with lower levels. I list some examples in <a href="https://www.excelmale.com/forum/threads/should-i-lower-my-trt-dose.24042/post-208106" target="_blank">this post</a>.</p><p></p><p>• Side effects are more likely, and we see far too many cases in which the side effects are treated separately when the obvious approach is to try a lower dose. Instead guys are struggling with finding the right AI dose to manage estradiol or with maintaining iron while giving blood often to manage high hematocrit.</p><p></p><p>• Most hormone levels have U-shaped mortality curves, meaning higher and lower levels are associated with reduced longevity. While the correlations do not necessarily indicate causality, there should be a pretty decent reward to make the possible risks acceptable. The possible risks extend to the downstream metabolites. Some men believe they can increase their testosterone to dose their way out of symptoms of high estrogen. While this may sometimes be possible, the long-term risks of having extremely high estradiol are also not known.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 209169, member: 38109"] I'm probably one to criticize high levels even more than [USER=13851]@madman[/USER]. Here are some of my objections: • Not always, but frequently, there's no attempt to give physiological levels a chance. The low-and-slow approach is ignored and guys start TRT with trough serum free/total testosterone that's near or over top-of-range. Typically this leads to peak levels that are considerably above normal physiology. Many guys end up regretting that they didn't start with lower levels. I list some examples in [URL='https://www.excelmale.com/forum/threads/should-i-lower-my-trt-dose.24042/post-208106']this post[/URL]. • Side effects are more likely, and we see far too many cases in which the side effects are treated separately when the obvious approach is to try a lower dose. Instead guys are struggling with finding the right AI dose to manage estradiol or with maintaining iron while giving blood often to manage high hematocrit. • Most hormone levels have U-shaped mortality curves, meaning higher and lower levels are associated with reduced longevity. While the correlations do not necessarily indicate causality, there should be a pretty decent reward to make the possible risks acceptable. The possible risks extend to the downstream metabolites. Some men believe they can increase their testosterone to dose their way out of symptoms of high estrogen. While this may sometimes be possible, the long-term risks of having extremely high estradiol are also not known. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Who feels better on e5d or e7d compared.to more frequent shots?
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