ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
When testicle size increases, what happens?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 176632" data-attributes="member: 13851"><p>LH stimulates the Leydig cells in the testes to produce ITT (intratesticular testosterone) and ITT/FSH stimulates the Sertoli/germ cells located inside the seminiferous tubule lobes to produce sperm.</p><p></p><p>When one uses exogenous testosterone/AAS it results in shut down of the HPG axis and the pituitary no longer secretes LH/FSH.</p><p></p><p>Lack of LH causes atrophy of the Leydig cells which are located between the seminiferous tubules and lack of ITT/FSH causes atrophy of the Sertoli/germ cells which are located inside the seminiferous tubules. The cells shrink and become dormant.</p><p></p><p>The body no longer produces endogenous testosterone and sperm production is halted.</p><p></p><p>The Leydig cells only make up 10-20% of testicular volume as oppose to the germ cells/seminiferous tubules (where sperm is produced) which make up almost 80% of the testicular volume so a majority of the shrinkage results from atrophy of the germ cells/seminiferous tubules.</p><p></p><p>Basically comes down to exogenous testosterone use results in significant suppression of spermatogenesis which leads to testicular shrinkage as a majority of teste volume is made up of germ cells located in the tightly bundled seminiferous tubule lobes where sperm is produced.</p><p></p><p>Not only does FSH stimulate sperm production but ITT alone is also playing a strong role.</p><p></p><p>Regarding the use of hCG we can take it along with trt to maintain fertility/prevent testicular shrinkage.</p><p></p><p>The use of hCG will mimic LH and result in stimulating the Leydig cells in the testes to produce ITT which will have a big impact on stimulating the Sertoli/germ cells located inside the seminiferous tubule lobes to produce sperm and this will cause an increase in testicular volume.</p><p></p><p>The use of Clomid stimulates LH and FSH which will increase testosterone/sperm production and maintain testicular size.</p></blockquote><p></p>
[QUOTE="madman, post: 176632, member: 13851"] LH stimulates the Leydig cells in the testes to produce ITT (intratesticular testosterone) and ITT/FSH stimulates the Sertoli/germ cells located inside the seminiferous tubule lobes to produce sperm. When one uses exogenous testosterone/AAS it results in shut down of the HPG axis and the pituitary no longer secretes LH/FSH. Lack of LH causes atrophy of the Leydig cells which are located between the seminiferous tubules and lack of ITT/FSH causes atrophy of the Sertoli/germ cells which are located inside the seminiferous tubules. The cells shrink and become dormant. The body no longer produces endogenous testosterone and sperm production is halted. The Leydig cells only make up 10-20% of testicular volume as oppose to the germ cells/seminiferous tubules (where sperm is produced) which make up almost 80% of the testicular volume so a majority of the shrinkage results from atrophy of the germ cells/seminiferous tubules. Basically comes down to exogenous testosterone use results in significant suppression of spermatogenesis which leads to testicular shrinkage as a majority of teste volume is made up of germ cells located in the tightly bundled seminiferous tubule lobes where sperm is produced. Not only does FSH stimulate sperm production but ITT alone is also playing a strong role. Regarding the use of hCG we can take it along with trt to maintain fertility/prevent testicular shrinkage. The use of hCG will mimic LH and result in stimulating the Leydig cells in the testes to produce ITT which will have a big impact on stimulating the Sertoli/germ cells located inside the seminiferous tubule lobes to produce sperm and this will cause an increase in testicular volume. The use of Clomid stimulates LH and FSH which will increase testosterone/sperm production and maintain testicular size. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
When testicle size increases, what happens?
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top