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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
What should be the next step? Stay on TRT?
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<blockquote data-quote="CoastWatcher" data-source="post: 28120" data-attributes="member: 2624"><p>In response to your questions.</p><p></p><p>1. Low SHBG can work against TRT success. It does not mean that it is impossible, however. Your total testosterone and free testosterone are actually solid. That would suggest you can make this work.</p><p></p><p>2. High prolactin and high estradiol work against libido and can certainly comtribute to erectile dysfunction. However, high E2 and high prolactin are two very different issues. Many men have high estradiol, they do not have high prolactin. Two very different things.</p><p></p><p>3. An AI will not reduce prolactin.</p><p></p><p>4. Pituitary tumours are rarely malignant.</p><p></p><p>5. There is a good chance you can work around the SHBG issue.</p><p></p><p>Your failure to respond to TRT are more than likely the result of high estradiol and elevated prolactin. An AI can deal with the former, an evaluation of your pituitary, followed by additional medication, is warranted to sort out the prolactin issue. I don't think you should abandon TRT. You just have additional medical issues to sort out.</p></blockquote><p></p>
[QUOTE="CoastWatcher, post: 28120, member: 2624"] In response to your questions. 1. Low SHBG can work against TRT success. It does not mean that it is impossible, however. Your total testosterone and free testosterone are actually solid. That would suggest you can make this work. 2. High prolactin and high estradiol work against libido and can certainly comtribute to erectile dysfunction. However, high E2 and high prolactin are two very different issues. Many men have high estradiol, they do not have high prolactin. Two very different things. 3. An AI will not reduce prolactin. 4. Pituitary tumours are rarely malignant. 5. There is a good chance you can work around the SHBG issue. Your failure to respond to TRT are more than likely the result of high estradiol and elevated prolactin. An AI can deal with the former, an evaluation of your pituitary, followed by additional medication, is warranted to sort out the prolactin issue. I don't think you should abandon TRT. You just have additional medical issues to sort out. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
What should be the next step? Stay on TRT?
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