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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What it the purpose of Sex Hormone Binding Globulin (SHBG) ?
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<blockquote data-quote="Dudley" data-source="post: 218658" data-attributes="member: 17180"><p>Thanks for this discussion and I agree with jacb that I wonder why high SHBG occurs and whether it is beneficial. By "high" I mean outside the reference range. Similarly, why does SHBG tend to rise as a man ages, what purpose is that serving? I am 67 and my high SHBG seems to impact my free testosterone so much that while my total T is right in the middle of the reference range, the free T is either below reference range or barely above it. This has been consistent over the several months I've had regular lab work with the recommended versions of tests from Discount Labs. A course of Clomid improved the numbers of my total T by a big margin, but also my SHBG by a notable margin, with the result being a minuscule impact on my free T. I realize that low SHBG is a serious problem, but I am very far away from that being an issue.</p></blockquote><p></p>
[QUOTE="Dudley, post: 218658, member: 17180"] Thanks for this discussion and I agree with jacb that I wonder why high SHBG occurs and whether it is beneficial. By "high" I mean outside the reference range. Similarly, why does SHBG tend to rise as a man ages, what purpose is that serving? I am 67 and my high SHBG seems to impact my free testosterone so much that while my total T is right in the middle of the reference range, the free T is either below reference range or barely above it. This has been consistent over the several months I've had regular lab work with the recommended versions of tests from Discount Labs. A course of Clomid improved the numbers of my total T by a big margin, but also my SHBG by a notable margin, with the result being a minuscule impact on my free T. I realize that low SHBG is a serious problem, but I am very far away from that being an issue. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What it the purpose of Sex Hormone Binding Globulin (SHBG) ?
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