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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
what is the real cause of finasteride /dutasteride induced gynecomastia ?
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<blockquote data-quote="Will Brink" data-source="post: 118173" data-attributes="member: 2074"><p>When you block one of several possible pathways (such as T to DHT) other pathways may compensate/up regulate, and 5ar inhibitors often sees a bump in E2 as that pathway has more substrate being pushed due to 5ar inhibition. Perhaps there's more current/advanced understanding of the effect since I looked, but that's the basic idea. I would not expect one to see gyno issues at your E2 levels. Is that via the sensitive test? Did you have gyno before? Those with pre existing gyno tend to be more sensitive to it. Why are you on the dutasteride? You'll not find many fans of that drug here.</p></blockquote><p></p>
[QUOTE="Will Brink, post: 118173, member: 2074"] When you block one of several possible pathways (such as T to DHT) other pathways may compensate/up regulate, and 5ar inhibitors often sees a bump in E2 as that pathway has more substrate being pushed due to 5ar inhibition. Perhaps there's more current/advanced understanding of the effect since I looked, but that's the basic idea. I would not expect one to see gyno issues at your E2 levels. Is that via the sensitive test? Did you have gyno before? Those with pre existing gyno tend to be more sensitive to it. Why are you on the dutasteride? You'll not find many fans of that drug here. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
what is the real cause of finasteride /dutasteride induced gynecomastia ?
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