Reply to thread

Message

Yes and yes.

Over close to 2 years, I have gone through repeated dosage reductions and have gone below what seems the minimum effective dose for me.

I have been through high HCT/HGB and E2, and slightly elevated E2 is an ongoing problem that I have to manage with micro dosed AI.

It takes 2-3 months for me to fully adjust to reductions, and getting to that kind of end point can be an exercise in abject misery. At a few weeks out, the withdrawl is at its worst for me. Due to the half life of T cyp, the typical theoretical amount of time it takes to reach a new steady state is 4-6 weeks, but for me, the body itself takes much longer to adapt.

My lowest effective dose is 84mg/week dosed 24mg EOD. I do use HCG 200iu EOD and anastrozole 0.06mg EOD.

[QUOTE="Deleted member 16042, post: 161953, member: 16042"] Yes and yes. Over close to 2 years, I have gone through repeated dosage reductions and have gone below what seems the minimum effective dose for me. I have been through high HCT/HGB and E2, and slightly elevated E2 is an ongoing problem that I have to manage with micro dosed AI. It takes 2-3 months for me to fully adjust to reductions, and getting to that kind of end point can be an exercise in abject misery. At a few weeks out, the withdrawl is at its worst for me. Due to the half life of T cyp, the typical theoretical amount of time it takes to reach a new steady state is 4-6 weeks, but for me, the body itself takes much longer to adapt. My lowest effective dose is 84mg/week dosed 24mg EOD. I do use HCG 200iu EOD and anastrozole 0.06mg EOD. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038