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Indeed. We must keep in mind that hCG is an analog of LH, but is NOT LH itself. Hence, there are *some* variations in downstream influences (mRNA expression, protein synthesis, etc). Unfortunately the only way to attempt to precisely mimic endogenous LH would be with a lyophilized LH product, but would have to be administered via an insulin pump-like apparatus owing to the short half life and pulsatile secretion pattern (unless willing to inject many times daily).