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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What is Optimal Estradiol Range for Libido/Erection
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<blockquote data-quote="madman" data-source="post: 171638" data-attributes="member: 13851"><p>People can keep going on speculating.....let alone claiming such!</p><p></p><p>The first testosterone assay was not developed until the late 1960's.</p><p></p><p>As I stated in a previous thread in my reply to a post from <span style="color: rgb(184, 49, 47)">davidrn</span>:</p><p>-----------------------------------------------------------------------------------------------------</p><p></p><p>[ATTACH=full]9230[/ATTACH]</p><p></p><p><a href="https://www.excelmale.com/forum/goto/post?id=161492" target="_blank">davidrn said:</a></p><p>"The normal range of testosterone is reported as 350- 1200ng/dl. <strong><span style="color: rgb(184, 49, 47)">Studies in the 1940's showed the average testosterone level to be at 700 ng/dl, 300 ng/dl higher than for men today.</span></strong> In the past, a drop in testosterone levels to 250 ng/dl was rarely reported before men were 80 years of age. Yet today, it is not an uncommon value for middle aged men! "</p><p><strong><span style="color: rgb(184, 49, 47)">I also have seen mention (assume this is estimated) that slim tradesmen as recent as a hundred years ago had levels up to the 2000 range. </span></strong>In my town, Italian stone workers built loose stone walls with little equipment in the 1870's, looking at pictures of these men, you realize how strong and wiry they were. What they weren't, was built like contemporary bodybuilders.</p><p>-----------------------------------------------------------------------------------------------------</p><p></p><p>My reply to <span style="color: rgb(184, 49, 47)">davidrn</span>:</p><p></p><p>There were no accurate testing methods decades ago.....let alone testing methods in the 1940's</p><p></p><p><a href="https://academic.oup.com/jcem/article/89/2/520/2840748" target="_blank">Serum Testosterone Assays—Accuracy Matters</a> (2004)</p><p><strong><span style="color: rgb(44, 130, 201)">The routine clinical use of T assays began approximately 30 yr ago with the development of RIAs for T that could be performed on relatively small quantities of blood after organic extraction and chromatographic separation (1). </span>Subsequently, there have been remarkable advancements in immunoassays for T as well as other hormones. Compared with original RIAs, T assays of today are more sensitive and specific, require smaller quantities of serum, do not involve extraction or chromatography, and are performed more rapidly and with less cost. In most large clinical chemistry and many reference laboratories, T assays are performed routinely on automated platforms using nonradioactive meth</strong></p><p></p><p></p><p></p><p><a href="http://eknygos.lsmuni.lt/springer/516/63-72.pdf" target="_blank">http://eknygos.lsmuni.lt/springer/516/63-72.pdf</a></p><p><strong>The first RIA method, developed in 1959 by Yallow and Berson (1,2), was for insulin. Ten years later, Abraham (3) reported the development of the first steroid RIA, which was for estradiol (E2). The immediate impact of the RIA method allowed measurement of an immensely wide range of compounds of clinical and biological importance and opened new horizons in endocrinology.</strong></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p><span style="color: rgb(184, 49, 47)">davidrn</span><span style="color: rgb(0, 0, 0)"> stated</span><strong><strong><span style="color: rgb(184, 49, 47)">....."I also have seen mention (assume this is estimated) that slim tradesmen as recent as a hundred years ago had levels up to the 2000 range"</span></strong></strong></p><p></p><p><strong><strong>-</strong></strong>that would be based off he said/she said!</p></blockquote><p></p>
[QUOTE="madman, post: 171638, member: 13851"] People can keep going on speculating.....let alone claiming such! The first testosterone assay was not developed until the late 1960's. As I stated in a previous thread in my reply to a post from [COLOR=rgb(184, 49, 47)]davidrn[/COLOR]: ----------------------------------------------------------------------------------------------------- [ATTACH=full]9230[/ATTACH] [URL='https://www.excelmale.com/forum/goto/post?id=161492']davidrn said:[/URL] "The normal range of testosterone is reported as 350- 1200ng/dl. [B][COLOR=rgb(184, 49, 47)]Studies in the 1940's showed the average testosterone level to be at 700 ng/dl, 300 ng/dl higher than for men today.[/COLOR][/B] In the past, a drop in testosterone levels to 250 ng/dl was rarely reported before men were 80 years of age. Yet today, it is not an uncommon value for middle aged men! " [B][COLOR=rgb(184, 49, 47)]I also have seen mention (assume this is estimated) that slim tradesmen as recent as a hundred years ago had levels up to the 2000 range. [/COLOR][/B]In my town, Italian stone workers built loose stone walls with little equipment in the 1870's, looking at pictures of these men, you realize how strong and wiry they were. What they weren't, was built like contemporary bodybuilders. ----------------------------------------------------------------------------------------------------- My reply to [COLOR=rgb(184, 49, 47)]davidrn[/COLOR]: There were no accurate testing methods decades ago.....let alone testing methods in the 1940's [URL='https://academic.oup.com/jcem/article/89/2/520/2840748']Serum Testosterone Assays—Accuracy Matters[/URL] (2004) [B][COLOR=rgb(44, 130, 201)]The routine clinical use of T assays began approximately 30 yr ago with the development of RIAs for T that could be performed on relatively small quantities of blood after organic extraction and chromatographic separation (1). [/COLOR]Subsequently, there have been remarkable advancements in immunoassays for T as well as other hormones. Compared with original RIAs, T assays of today are more sensitive and specific, require smaller quantities of serum, do not involve extraction or chromatography, and are performed more rapidly and with less cost. In most large clinical chemistry and many reference laboratories, T assays are performed routinely on automated platforms using nonradioactive meth[/B] [URL]http://eknygos.lsmuni.lt/springer/516/63-72.pdf[/URL] [B]The first RIA method, developed in 1959 by Yallow and Berson (1,2), was for insulin. Ten years later, Abraham (3) reported the development of the first steroid RIA, which was for estradiol (E2). The immediate impact of the RIA method allowed measurement of an immensely wide range of compounds of clinical and biological importance and opened new horizons in endocrinology.[/B] [COLOR=rgb(184, 49, 47)]davidrn[/COLOR][COLOR=rgb(0, 0, 0)] stated[/COLOR][B][B][COLOR=rgb(184, 49, 47)]....."I also have seen mention (assume this is estimated) that slim tradesmen as recent as a hundred years ago had levels up to the 2000 range"[/COLOR][/B][/B] [B][B]-[/B][/B]that would be based off he said/she said! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What is Optimal Estradiol Range for Libido/Erection
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