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Here's the theory (very hard to find my old stuff on here; only have myself to blame):

[URL unfurl="true"]https://www.excelmale.com/threads/hcg-plus-androgens-other-than-test.25623/post-232877[/URL]

You only have single points in time. What you would like to know is area under curve (AUC). In the absence of additional info you know that AUC for fT is proportional to dose. It is probably pretty close for both cases (you are going through the same mg of testosterone each week). But there is some variation in your serum concentrations over the week (exercise vs no exercise) as your single data points show; your liver clears the T faster or slower which changes your elimination rate constant. There is also the term called distribution volume.

I wouldn't worry about it. But if the single time point is concerning then do what makes you comfortable.

<blockquote data-quote="aloetard" data-source="post: 286927" data-attributes="member: 47160">Here&#039;s the theory (very hard to find my old stuff on here; only have myself to blame):[URL unfurl=&quot;true&quot;]https://www.excelmale.com/threads/hcg-plus-androgens-other-than-test.25623/post-232877[/URL]You only have single points in time.&nbsp; What you would like to know is area under curve (AUC).&nbsp; In the absence of additional info you know that AUC for fT is proportional to dose.&nbsp; It is probably pretty close for both cases (you are going through the same mg of testosterone each week).&nbsp; But there is some variation in your serum concentrations over the week (exercise vs no exercise) as your single data points show; your liver clears the T faster or slower which changes your elimination rate constant.&nbsp; There is also the term called distribution volume. &nbsp;I wouldn&#039;t worry about it.&nbsp; But if the single time point is concerning then do what makes you comfortable.</blockquote>

[QUOTE="aloetard, post: 286927, member: 47160"] Here's the theory (very hard to find my old stuff on here; only have myself to blame): [URL unfurl="true"]https://www.excelmale.com/threads/hcg-plus-androgens-other-than-test.25623/post-232877[/URL] You only have single points in time. What you would like to know is area under curve (AUC). In the absence of additional info you know that AUC for fT is proportional to dose. It is probably pretty close for both cases (you are going through the same mg of testosterone each week). But there is some variation in your serum concentrations over the week (exercise vs no exercise) as your single data points show; your liver clears the T faster or slower which changes your elimination rate constant. There is also the term called distribution volume. I wouldn't worry about it. But if the single time point is concerning then do what makes you comfortable. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038