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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What does low shbg actually mean ?
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<blockquote data-quote="TRicker" data-source="post: 216940" data-attributes="member: 42831"><p>I'd like to know the same, if anyone can answer.</p><p>I know I've read (possibly a theory) that low shbg reduces androgen action without reducing estrogen action...meaning a skewed higher estrogen to testosterone ratio.</p><p>I've also read (possible theory) that shbg transports the androgens, and if it's low it can't get the test to where it needs to be.</p><p></p><p>I too, have low shbg, most likely due to trt. It hovers around 16-17, and if I take a break from trt for a month, it creeps back up to 23-25. I just did an enclomiphene trial for 5 months for fertility reasons (25mg/day of enclomiphene), and after 18 weeks my shbg was 30. Now I'm on 100mg per week of (50mg every 3.5 days), and my shbg is back to 16, and I don't feel it. I did have a brief honeymoon period going back to trt from enclomiphene, but it only lasted a week.</p><p></p><p>The funny thing is, 8 years ago, before I knew any better, my trt clinic had me on 200mg per week in one shot, and I felt better. Of course it's a large dose, and my shbg was low then also, but maybe the larger dose just somehow overcame other problems? As somebody else pointed out, there's plenty of steroid abusers who crush their shbg levels, yet feel great.</p><p></p><p>So is the T just not getting to where it needs to? Is the low shbg causing high free E2, and skewing the free E2/Free T ratio? Is it something else that makes low shbg problematic?</p></blockquote><p></p>
[QUOTE="TRicker, post: 216940, member: 42831"] I'd like to know the same, if anyone can answer. I know I've read (possibly a theory) that low shbg reduces androgen action without reducing estrogen action...meaning a skewed higher estrogen to testosterone ratio. I've also read (possible theory) that shbg transports the androgens, and if it's low it can't get the test to where it needs to be. I too, have low shbg, most likely due to trt. It hovers around 16-17, and if I take a break from trt for a month, it creeps back up to 23-25. I just did an enclomiphene trial for 5 months for fertility reasons (25mg/day of enclomiphene), and after 18 weeks my shbg was 30. Now I'm on 100mg per week of (50mg every 3.5 days), and my shbg is back to 16, and I don't feel it. I did have a brief honeymoon period going back to trt from enclomiphene, but it only lasted a week. The funny thing is, 8 years ago, before I knew any better, my trt clinic had me on 200mg per week in one shot, and I felt better. Of course it's a large dose, and my shbg was low then also, but maybe the larger dose just somehow overcame other problems? As somebody else pointed out, there's plenty of steroid abusers who crush their shbg levels, yet feel great. So is the T just not getting to where it needs to? Is the low shbg causing high free E2, and skewing the free E2/Free T ratio? Is it something else that makes low shbg problematic? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What does low shbg actually mean ?
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