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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Water retention when I inject @ evening and less when @ morning, ideas why ?
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<blockquote data-quote="madman" data-source="post: 190994" data-attributes="member: 13851"><p>During the 24hr circadian rhythm of a healthy young male testosterone level will start to increase gradually overnight reaching peak levels between 6-8 am and by 11-12 pm will start to decline late afternoon/early evening reaching a trough between 6-8 pm.</p><p></p><p>Fluctuations from peak--->trough would be around 20-25%</p><p></p><p>Natural T levels <span style="color: rgb(184, 49, 47)"><u>follow a diurnal 24 hr circadian rhythm and will <strong>start to rise gradually overnight</strong> reaching peak levels around 8 am</u></span></p><p></p><p>Natural endogenous testosterone secretion is pulsatile and diurnal.</p><p></p><p>A large percentage of men are using intramuscular/subcutaneous injections using various injection protocol (once weekly, twice weekly, M/W/F, EOD, daily) and in no way are mimicking the natural 24hr circadian rhythm of a healthy young male.</p><p></p><p><span style="color: rgb(184, 49, 47)"><u><strong>Steady-state, many are running levels well into the supra-physiological range 24/7 let alone the hpta is shutdown</strong></u>.</span></p><p></p><p>The closest you could get to mimicking the natural 24hr circadian rhythm would be using the T patch or transdermal but again your hpta is still shutdown.</p><p></p><p>Top it off with the fact that when using exogenous T we are forcing levels upon ourselves that the body would never produce naturally.</p><p></p><p>Regardless of the ester used (prop/enanthate/cyp) <span style="color: rgb(184, 49, 47)"><u><strong>T levels will start rising within the first 2 hrs as there is an initial burst release</strong></u> </span>and even when using prop Tmax will be reached much sooner than most would think.</p><p></p><p>No way you are mimicking the natural 24 hr circadian rhythm even on daily prop injections.</p><p></p><p></p><p></p><p></p><p></p><p>You need to sit back and rethink this trying to mimic the natural 24 hr circadian rhythm using short-acting esterified injectable T (daily injections).</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/short-acting-t-therapy-to-maintain-homeostasis-that-more-closely-reflects-normal-physiology.22083/[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 190994, member: 13851"] During the 24hr circadian rhythm of a healthy young male testosterone level will start to increase gradually overnight reaching peak levels between 6-8 am and by 11-12 pm will start to decline late afternoon/early evening reaching a trough between 6-8 pm. Fluctuations from peak--->trough would be around 20-25% Natural T levels [COLOR=rgb(184, 49, 47)][U]follow a diurnal 24 hr circadian rhythm and will [B]start to rise gradually overnight[/B] reaching peak levels around 8 am[/U][/COLOR] Natural endogenous testosterone secretion is pulsatile and diurnal. A large percentage of men are using intramuscular/subcutaneous injections using various injection protocol (once weekly, twice weekly, M/W/F, EOD, daily) and in no way are mimicking the natural 24hr circadian rhythm of a healthy young male. [COLOR=rgb(184, 49, 47)][U][B]Steady-state, many are running levels well into the supra-physiological range 24/7 let alone the hpta is shutdown[/B][/U].[/COLOR] The closest you could get to mimicking the natural 24hr circadian rhythm would be using the T patch or transdermal but again your hpta is still shutdown. Top it off with the fact that when using exogenous T we are forcing levels upon ourselves that the body would never produce naturally. Regardless of the ester used (prop/enanthate/cyp) [COLOR=rgb(184, 49, 47)][U][B]T levels will start rising within the first 2 hrs as there is an initial burst release[/B][/U] [/COLOR]and even when using prop Tmax will be reached much sooner than most would think. No way you are mimicking the natural 24 hr circadian rhythm even on daily prop injections. You need to sit back and rethink this trying to mimic the natural 24 hr circadian rhythm using short-acting esterified injectable T (daily injections). [URL unfurl="true"]https://www.excelmale.com/forum/threads/short-acting-t-therapy-to-maintain-homeostasis-that-more-closely-reflects-normal-physiology.22083/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Water retention when I inject @ evening and less when @ morning, ideas why ?
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