Vitamin D and male sexual function



Table of Contents


Background


The effects of vitamin D on sexual function are very unclear. Therefore, we aimed at evaluating the possible association between vitamin D and sexual function and at assessing the influence of vitamin D administration on sexual function.

Methods


We retrospectively studied 114 men by evaluating clinical, biochemical, and sexual parameters.
A subsample () was also studied longitudinally before and after vitamin D replacement therapy.

Results


In the whole sample, after performing logistic regression models, higher levels of 25(OH) vitamin D were significantly associated with high values of total testosterone and of all the International Index of Erectile Function (IIEF) questionnaire parameters.
On the other hand, higher levels of total testosterone were positively and significantly associated with high levels of erectile function and IIEF total score.
After vitamin D replacement therapy, total and free testosterone increased and erectile function improved, whereas other sexual parameters did not change significantly.
At logistic regression analysis, higher levels of vitamin D increase (?-) were significantly associated with high values of ?-erectile function after adjustment for ?-testosterone.

Conclusions


Vitamin D is important for the wellness of male sexual function, and vitamin D administration improves sexual function.
https://www.hindawi.com/journals/ije/2018/3720813/
 

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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