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Low IGFBP-3 and IGF-1 levels are typically observed in GH deficiency or GH resistance. Now getting a prescription for HGH is almost impossible unless you have the following:

1. HGH deficiency in children might result in dwarfism
2. Adult HGH deficiency due to tumors in the brain and their treatment like radiation therapy
3. Muscle wasting illness related to HIV/AIDs

My suggestion is using peptides or even MK 677 to get the GH levels up, thus the IGF-1 IGFBP-3 levels also increase.  Of course as you said, DEFY is not selling what you need.,   What they do have is Sermorelin, and Sarcotropin which are both GHRHs.   The other option, PT-141 is not going to help at all.  The other two GHRHs have very short half lives (<5min) so are the GH response is very weak, plus as IGF-1 levels rise, somatotropin can shut the pituitary output of GH down. So the results you get will be very minimal.   This is why we always suggest taking a GHRP with a GHRH to help avoid rises in somatotropin and keep the pituitary pulsing an abundance of GH.   You would be much better taking MK 677 with is similar in action to a GHRP or taking Modified GRF (1-29) and a GHRP (Ipamorelin, GHRP 2, GHRP 6 or Hexarelin).   These can be much more cheaply found at a peptide store on the internet.