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Very high T and SHBG
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<blockquote data-quote="RyanW" data-source="post: 107255" data-attributes="member: 18371"><p><span style="color: #333333">Was on Sertraline at the time these labs but have since gone off successfully so far.</span></p><p><span style="color: #333333">My primary complaint is fatigue, exhaustion and lack of desire to do anything including fun including sex.</span></p><p><span style="color: #333333"></span></p><p><span style="color: #333333">I am not taking any supplements and eat a healthy diet, overall very healthy. </span></p><p><span style="color: #333333"></span></p><p><span style="color: #333333">Testosterone: 1995 ng/dL (0.320-1100)</span></p><p><span style="color: #333333">Free Testosterone: 133.7 (35.0-155.0)</span></p><p><span style="color: #333333">SHBG: 146 nmol/L (10-50)</span></p><p><span style="color: #333333">Prolactin: 17.4 ng/ml (Not listed)</span></p><p><span style="color: #333333">THS: 3.871 ilU.L (0.320-5.550)</span></p><p><span style="color: #333333">Estradoil: 50pg/ml (Not listed) BUT flagged as “High”</span></p><p><span style="color: #333333">DHEA: 217 us.dL (Not listed)</span></p><p><span style="color: #333333">FSH: 7.4miU/ml (Not listed)</span></p><p><span style="color: #333333">LH: 8.3mIU/ml (Not listed)</span></p><p><span style="color: #333333">T3F 2.79 (2.3-4.2)</span></p><p><span style="color: #333333">T4F 1.40 (.50 -2.50)</span></p><p><span style="color: #333333">T3, reverse 22 (8 - 25)</span></p><p><span style="color: #333333"></span></p><p><span style="color: #333333"></span>Liver, Kidney and CBC normal</p><p><span style="color: #333333">Testicular ultrasound negative, BetaHtcgtm negative,</span></p><p><span style="color: #333333"><strong></strong></span></p><p><span style="color: #333333"><strong>HERE IS MY ENDOCRINOLOGIST'S FINDINGS</strong> She had nothing to say about my thyroid or sertaline being a problem</span></p><p><span style="color: #333333"><em>As we reviewed today:</em></span></p><p><span style="color: #333333"><em>->your total testosterone is elevated but this is because SHBG (sex hormone binding globulin) the carrier protein for testosterone is elevated (in fact the free testosterone is normal)</em></span></p><p><span style="color: #333333">_ _</span></p><p><span style="color: #333333"><em>->other hormone testing is also normal with the exception of estradiol being slightly elevated = which is likely the culprit for the elevated SHBG testing</em></span></p><p><span style="color: #333333">_ _</span></p><p><span style="color: #333333"><em>->in terms of the etiology for the slightly elevated estradiol=your testicular ultrasound and HCG testing is normal so this is not coming from the testicles per se. I recommend a CT scan of the adrenal glands to verify that there is no abnormality in the adrenal glands (which is another source of estradiol precursors so can potentially cause elevated estradiol). In the end if all the additional testing is normal, then by diagnosis of exclusion the elevated estradiol is coming from increased extraglandular aromatase activity. That said, for a few years I will recommend your primary care doctor continue to assess your hormone levels periodically</em></span></p><p><span style="color: #333333">_ _</span></p><p><span style="color: #333333"><em>->unfortunately this doesn't explain why you are felling unwell which is why you sought medical attention in the first place, I recommend some 8-9 am fasting blood work (additional testing to rule out contributing factors that could be implicated in your fatigue symptoms)</em></span></p><p><span style="color: #333333">_ _</span></p><p><span style="color: #333333"><em>->I recommend you have a sleep study to rule out potential sleep apnea,</em></span></p><p><span style="color: #333333">She ordered cortisol, Kidney function B12 and Vit D also ordered a CT of my adrenals and brainstem.</span></p></blockquote><p></p>
[QUOTE="RyanW, post: 107255, member: 18371"] [COLOR=#333333][FONT=Helvetica]Was on Sertraline at the time these labs but have since gone off successfully so far.[/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica]My primary complaint is fatigue, exhaustion and lack of desire to do anything including fun including sex.[/FONT] [FONT=Helvetica]I am not taking any supplements and eat a healthy diet, overall very healthy. [/FONT] [/COLOR] [COLOR=#333333][FONT=Helvetica]Testosterone: 1995 ng/dL (0.320-1100)[/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica]Free Testosterone: 133.7 (35.0-155.0) SHBG: 146 nmol/L (10-50) Prolactin: 17.4 ng/ml (Not listed) THS: 3.871 ilU.L (0.320-5.550) Estradoil: 50pg/ml (Not listed) BUT flagged as “High” DHEA: 217 us.dL (Not listed) FSH: 7.4miU/ml (Not listed) LH: 8.3mIU/ml (Not listed)[/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica]T3F 2.79 (2.3-4.2) T4F 1.40 (.50 -2.50) T3, reverse 22 (8 - 25) [/FONT][/COLOR]Liver, Kidney and CBC normal [COLOR=#333333][FONT=Helvetica]Testicular ultrasound negative, BetaHtcgtm negative,[/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica][B] HERE IS MY ENDOCRINOLOGIST'S FINDINGS[/B] She had nothing to say about my thyroid or sertaline being a problem[/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica][I]As we reviewed today:[/I] [I]->your total testosterone is elevated but this is because SHBG (sex hormone binding globulin) the carrier protein for testosterone is elevated (in fact the free testosterone is normal)[/I] _ _ [I]->other hormone testing is also normal with the exception of estradiol being slightly elevated = which is likely the culprit for the elevated SHBG testing[/I] _ _ [I]->in terms of the etiology for the slightly elevated estradiol=your testicular ultrasound and HCG testing is normal so this is not coming from the testicles per se. I recommend a CT scan of the adrenal glands to verify that there is no abnormality in the adrenal glands (which is another source of estradiol precursors so can potentially cause elevated estradiol). In the end if all the additional testing is normal, then by diagnosis of exclusion the elevated estradiol is coming from increased extraglandular aromatase activity. That said, for a few years I will recommend your primary care doctor continue to assess your hormone levels periodically[/I] _ _ [I]->unfortunately this doesn't explain why you are felling unwell which is why you sought medical attention in the first place, I recommend some 8-9 am fasting blood work (additional testing to rule out contributing factors that could be implicated in your fatigue symptoms)[/I] _ _ [I]->I recommend you have a sleep study to rule out potential sleep apnea,[/I][/FONT][/COLOR] [COLOR=#333333][FONT=Helvetica]She ordered cortisol, Kidney function B12 and Vit D also ordered a CT of my adrenals and brainstem.[/FONT][/COLOR] [/QUOTE]
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Very high T and SHBG
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