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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Very high FT on 70mg/wk?
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<blockquote data-quote="JustPanicNoDisco" data-source="post: 219892" data-attributes="member: 42100"><p>No, unfortunately I did not. I actually plugged in my results to an online calculator to assess SHBG (figuring it must be extremely low) after receiving these results. The calculators, however, are pretty useless, since units/volume and their associates ranges very wildly across technique. It would surely be interesting.</p><p></p><p>I know dialysis is the method always championed on this website, but science seems to believe the different test methods correlate very highly (r > 96).</p><p></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/24090209/[/URL]</p><p></p><p>In the past I’ve used mostly calculated or LC/MS, I believe, which could potentially account for differences in results, but I still doubt it. Daily shots should keep SHBG higher, if anything.</p><p></p><p>As for estrogen supplementation, my concern is that it may cause (permanent or semi-permanent) changes to aromatase production. I don’t know exactly whats underpinning the lasting low E2 sides many experience after crashing their estrogen as serum numbers seem to rebound while symptoms remain. I just don’t want to take on unnecessary risk worsening this (but also cannot exactly live in this state)</p><p></p><p>I’m not sure if there is any literature that tests how exogenous estro influences aromatase expression.</p><p></p><p>I would definitely start slow. Thanks for the resource. Typing on mobile. Apologies for formatting / typos.</p></blockquote><p></p>
[QUOTE="JustPanicNoDisco, post: 219892, member: 42100"] No, unfortunately I did not. I actually plugged in my results to an online calculator to assess SHBG (figuring it must be extremely low) after receiving these results. The calculators, however, are pretty useless, since units/volume and their associates ranges very wildly across technique. It would surely be interesting. I know dialysis is the method always championed on this website, but science seems to believe the different test methods correlate very highly (r > 96). [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/24090209/[/URL] In the past I’ve used mostly calculated or LC/MS, I believe, which could potentially account for differences in results, but I still doubt it. Daily shots should keep SHBG higher, if anything. As for estrogen supplementation, my concern is that it may cause (permanent or semi-permanent) changes to aromatase production. I don’t know exactly whats underpinning the lasting low E2 sides many experience after crashing their estrogen as serum numbers seem to rebound while symptoms remain. I just don’t want to take on unnecessary risk worsening this (but also cannot exactly live in this state) I’m not sure if there is any literature that tests how exogenous estro influences aromatase expression. I would definitely start slow. Thanks for the resource. Typing on mobile. Apologies for formatting / typos. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Very high FT on 70mg/wk?
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