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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
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<blockquote data-quote="Cataceous" data-source="post: 216522" data-attributes="member: 38109"><p>I don't recall seeing this particular hypothesis. It seems like a stretch. However, I have speculated that the best testosterone level for a particular individual has as good of a chance of being below the mean as above it. "Best" level in this case encompasses the compromises that lead to balanced hormones and good subjective results. </p><p></p><p>The typical scenario is that a new guy comes here having been prescribed 100-200 mg T cypionate per week. He has trough testosterone that is well above the mean for healthy young men, and he has one or more symptoms of high testosterone, such as elevated hematocrit, poor lipids, or high estradiol. His subjective results are typically poor as well. So yes, the advice in these cases is to try lowering the dose—and in the absence of better information, to target average levels for healthy young men. And no, it's not explicitly stated that "all/most all" side effects will resolve. But there's a good chance the side effects linked to excessive testosterone will improve. Are you saying this is questionable advice?</p><p></p><p>The main problem with the advice is the limit on what can be achieved by adjusting one variable. If HPTA shutdown causes symptoms then they are not going to be resolved by taking modestly less testosterone. There's also the hypothetical scenario in which high-T symptoms don't resolve with lower dosing before low-T symptoms recur. I don't know if this has occurred in practice, but if so it also points to the limits of conventional TRT.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 216522, member: 38109"] I don't recall seeing this particular hypothesis. It seems like a stretch. However, I have speculated that the best testosterone level for a particular individual has as good of a chance of being below the mean as above it. "Best" level in this case encompasses the compromises that lead to balanced hormones and good subjective results. The typical scenario is that a new guy comes here having been prescribed 100-200 mg T cypionate per week. He has trough testosterone that is well above the mean for healthy young men, and he has one or more symptoms of high testosterone, such as elevated hematocrit, poor lipids, or high estradiol. His subjective results are typically poor as well. So yes, the advice in these cases is to try lowering the dose—and in the absence of better information, to target average levels for healthy young men. And no, it's not explicitly stated that "all/most all" side effects will resolve. But there's a good chance the side effects linked to excessive testosterone will improve. Are you saying this is questionable advice? The main problem with the advice is the limit on what can be achieved by adjusting one variable. If HPTA shutdown causes symptoms then they are not going to be resolved by taking modestly less testosterone. There's also the hypothetical scenario in which high-T symptoms don't resolve with lower dosing before low-T symptoms recur. I don't know if this has occurred in practice, but if so it also points to the limits of conventional TRT. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
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