ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="tareload" data-source="post: 216472"><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392149/[/URL]</p><p>[URL unfurl="true"]https://www.mdpi.com/2073-4409/10/8/2067[/URL]</p><p>[URL unfurl="true"]https://www.mdpi.com/2073-4409/10/8/2067/s1[/URL]</p><p></p><p>[ATTACH=full]19388[/ATTACH]</p><p></p><p></p><p></p><p></p><p>[ATTACH=full]19390[/ATTACH]</p><p></p><p>[ATTACH=full]19399[/ATTACH]</p><p></p><p></p><p></p><p>From the list, here's the study with highest change in TT upon treatment (Knapp 2008):</p><p></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/18430965/[/URL]</p><p></p><p>[URL unfurl="true"]https://journals.physiology.org/doi/pdf/10.1152/ajpendo.90213.2008[/URL]</p><p></p><p>Interesting...these folks were hitting ~1000 ng/dl at trough with weekly injections of 300 mg (16 weeks):</p><p></p><p>[ATTACH=full]19394[/ATTACH]</p><p>[ATTACH=full]19393[/ATTACH]</p><p>[ATTACH=full]19392[/ATTACH]</p><p></p><p>Comments on safety:</p><p>[ATTACH=full]19395[/ATTACH]</p><p>[ATTACH=full]19396[/ATTACH]</p><p></p><p></p><p>Study power:</p><p>[ATTACH=full]19397[/ATTACH]</p><p></p><p></p><p>In summary, I haven't yet found the long term studies you mention. <em>I do see one study which most likely pushed serum peak TT levels to up to ~2000 ng/dl as the trough measured up to 1000 ng/dl (weekly injections of 300 mg/week Test ester). Almost all of these studies simulate something much less than a single Test cycle or blast once you trace back what the weekly dosing did to the serum TT level (see Supplementary Fig S3 Panel A). All of the studies summarized above are short. </em></p><p></p><p>Obviously, these are potentially life-saving interventions for people with wasting disease. However, I'll await your claimed data for long-term studies. Maybe we are operating under different definitions of long term.</p><p></p><p>See for example:</p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/19167590/[/URL]</p><p></p><p>Hey, even one year would be nice.</p></blockquote><p></p>
[QUOTE="tareload, post: 216472"] [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392149/[/URL] [URL unfurl="true"]https://www.mdpi.com/2073-4409/10/8/2067[/URL] [URL unfurl="true"]https://www.mdpi.com/2073-4409/10/8/2067/s1[/URL] [ATTACH type="full" width="623px" alt="1643593591396.png"]19388[/ATTACH] [ATTACH type="full" alt="1643594016748.png"]19390[/ATTACH] [ATTACH type="full" alt="1643596024712.png"]19399[/ATTACH] From the list, here's the study with highest change in TT upon treatment (Knapp 2008): [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/18430965/[/URL] [URL unfurl="true"]https://journals.physiology.org/doi/pdf/10.1152/ajpendo.90213.2008[/URL] Interesting...these folks were hitting ~1000 ng/dl at trough with weekly injections of 300 mg (16 weeks): [ATTACH type="full" alt="1643594811508.png"]19394[/ATTACH] [ATTACH type="full" alt="1643594697014.png"]19393[/ATTACH] [ATTACH type="full" alt="1643594534708.png"]19392[/ATTACH] Comments on safety: [ATTACH type="full" alt="1643594928052.png"]19395[/ATTACH] [ATTACH type="full" alt="1643594952627.png"]19396[/ATTACH] Study power: [ATTACH type="full" alt="1643595026507.png"]19397[/ATTACH] In summary, I haven't yet found the long term studies you mention. [I]I do see one study which most likely pushed serum peak TT levels to up to ~2000 ng/dl as the trough measured up to 1000 ng/dl (weekly injections of 300 mg/week Test ester). Almost all of these studies simulate something much less than a single Test cycle or blast once you trace back what the weekly dosing did to the serum TT level (see Supplementary Fig S3 Panel A). All of the studies summarized above are short. [/I] Obviously, these are potentially life-saving interventions for people with wasting disease. However, I'll await your claimed data for long-term studies. Maybe we are operating under different definitions of long term. See for example: [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/19167590/[/URL] Hey, even one year would be nice. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top