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TRT shot frequency
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<blockquote data-quote="Cataceous" data-source="post: 246833" data-attributes="member: 38109"><p>I agree that in the long run it's better to inject less frequently if you can get away with it. However, there is an argument in favor of starting out with frequent injections: such a protocol makes it easy to determine your response to varying doses. Our general expectation is that after you've reached a steady state your free testosterone will be proportional to your dose rate:</p><p>FT = k * D</p><p>If you know your "k" value then you can predict your testosterone levels at different doses. This constant is most accurately determined if you have minimal variation in serum testosterone. With twice-weekly injections of testosterone cypionate there is still substantial variation in serum testosterone, with peaks as much as 50-60% above troughs. This makes it difficult to estimate your average level. With daily and maybe EOD injections, serum testosterone is usually pretty stable, and measurements at any time are a reasonable reflection of average levels.</p><p></p><p>One other bonus in starting with frequent injections is that you then have a frame of reference for what static testosterone feels like. Then you can contrast it with the variation you'll experience with twice-weekly injections. Neither protocol is exactly in line with normal physiology. It's more natural to have a diurnal rhythm, meaning you get pretty significant variation over the course of each day, but not large, multi-day swings.</p><p></p><p>Only you can decide if having the extra information is worth the effort.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 246833, member: 38109"] I agree that in the long run it's better to inject less frequently if you can get away with it. However, there is an argument in favor of starting out with frequent injections: such a protocol makes it easy to determine your response to varying doses. Our general expectation is that after you've reached a steady state your free testosterone will be proportional to your dose rate: FT = k * D If you know your "k" value then you can predict your testosterone levels at different doses. This constant is most accurately determined if you have minimal variation in serum testosterone. With twice-weekly injections of testosterone cypionate there is still substantial variation in serum testosterone, with peaks as much as 50-60% above troughs. This makes it difficult to estimate your average level. With daily and maybe EOD injections, serum testosterone is usually pretty stable, and measurements at any time are a reasonable reflection of average levels. One other bonus in starting with frequent injections is that you then have a frame of reference for what static testosterone feels like. Then you can contrast it with the variation you'll experience with twice-weekly injections. Neither protocol is exactly in line with normal physiology. It's more natural to have a diurnal rhythm, meaning you get pretty significant variation over the course of each day, but not large, multi-day swings. Only you can decide if having the extra information is worth the effort. [/QUOTE]
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