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No! Not a metabolite. Remember that testosterone and estradiol are tiny molecules compared to prolactin. Estradiol is simply one of many factors that influence the production rate of prolactin, and estradiol is stimulatory rather than inhibitory.

There are a few conditions other than prolactinomas that may be associated with hyperprolactinemia. As prolactin is regulated by dopamine , medications that interfere with this substance in the brain can cause elevated prolactin levels. Drugs prescribed for psychiatric and gastrointestinal disorders may raise prolactin levels to greater than 200 ng/ ml. Other drugs that can cause mild elevations of prolactin levels include estrogens and verapamil, a drug used to treat high blood pressure.

An underactive thyroid or inadequate thyroid hormone replacement can also raise prolactin levels, as can kidney disease, pregnancy, stress, and chest trauma.

[URL unfurl="true"]https://pituitarysociety.org/patient-education/pituitary-disorders/prolactinoma/what-else-can-cause-elevated-prolactin-levels[/URL]