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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
TRT effect on Thrombocytopenia and platelet counts
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<blockquote data-quote="Nelson Vergel" data-source="post: 273965" data-attributes="member: 3"><p>I found this.</p><p></p><p>Testosterone has been found to have complex effects on platelet function. Some studies suggest that testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women, indicating an inhibitory action on blood platelets[1]. However, other research has demonstrated that testosterone increases human platelet thromboxane A2 receptor density, which may contribute to enhanced thrombus formation[2][3]. Additionally, physiological concentrations of testosterone have been shown to stimulate endothelial cell growth and inhibit platelet aggregation through its direct action on endothelial nitric oxide production[4]. Furthermore, testosterone administration has been associated with a significant increase in the platelet count[5]. These findings indicate that the relationship between testosterone and thrombocytopenia is complex and may involve multiple mechanisms.</p><p></p><p>Citations:</p><p>[1] <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990384/" target="_blank">Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women</a></p><p>[2] <a href="https://www.ahajournals.org/doi/full/10.1161/01.cir.91.11.2742" target="_blank">https://www.ahajournals.org/doi/full/10.1161/01.cir.91.11.2742</a></p><p>[3] <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795962/" target="_blank">Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review</a></p><p>[4] <a href="https://joe.bioscientifica.com/downloadpdf/view/journals/joe/213/1/77.pdf" target="_blank">https://joe.bioscientifica.com/downloadpdf/view/journals/joe/213/1/77.pdf</a></p><p>[5] <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12834" target="_blank">https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12834</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 273965, member: 3"] I found this. Testosterone has been found to have complex effects on platelet function. Some studies suggest that testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women, indicating an inhibitory action on blood platelets[1]. However, other research has demonstrated that testosterone increases human platelet thromboxane A2 receptor density, which may contribute to enhanced thrombus formation[2][3]. Additionally, physiological concentrations of testosterone have been shown to stimulate endothelial cell growth and inhibit platelet aggregation through its direct action on endothelial nitric oxide production[4]. Furthermore, testosterone administration has been associated with a significant increase in the platelet count[5]. These findings indicate that the relationship between testosterone and thrombocytopenia is complex and may involve multiple mechanisms. Citations: [1] [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990384/"]Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women[/URL] [2] [URL]https://www.ahajournals.org/doi/full/10.1161/01.cir.91.11.2742[/URL] [3] [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795962/"]Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review[/URL] [4] [URL]https://joe.bioscientifica.com/downloadpdf/view/journals/joe/213/1/77.pdf[/URL] [5] [URL]https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12834[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
TRT effect on Thrombocytopenia and platelet counts
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