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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety?
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<blockquote data-quote="madman" data-source="post: 203858" data-attributes="member: 13851"><p>Most definitely.</p><p></p><p>I would still like to see more men test upstream hormones (LC/MS-MS) after using high enough doses of hCG at least 250-500IU injected EOD as such doses are most likely needed to fully restore physiological ITT levels.</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/hormone-panel-for-men-on-trt-comprehensive[/URL]</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/pregnenolone[/URL]</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/progesterone[/URL]</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/17-oh-progesterone-hcg-efficacy-predictor[/URL]</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/dhea-sulfate[/URL]</p><p></p><p>The goal should be to restore <em><strong>physiological ITT levels</strong></em> which may very well be needed to reap the full beneficial effects let alone to prevent disruption of upstream hormones!</p><p></p><p>Unfortunately, many may struggle with sides on such protocol (dose/injection frequency).</p><p></p><p>No point in stating/claiming that the addition of hCG has no impact on upstream hormones when you have never used high enough doses let alone tested using an accurate assay.</p><p></p><p></p><p></p><p><strong>5.1 Effects on intratesticular testosterone</strong></p><p><strong></strong></p><p><strong><em>Exogenous testosterone administration suppresses intratesticular testosterone (ITT), which is crucial for the production of sperm [24]. <u>IN SUCH PATIENTS, ITT HAS BEEN SHOWN TO BE SUPPRESSED BY 94%</u>. <u>However, with every other day injections of HCG at dosages of 125IU, ITT was only 25% LESS THAN BASELINE, with 250IU 7% LESS and with 500IU 26% GREATER THAN THE BASELINE</u> [25].</em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em>*These studies indicate that HCG can significantly increase ITT in a dose-dependent manner and that <u>dosages between 250 and 500 IU might be optimal to restore physiological ITT levels</u>.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 203858, member: 13851"] Most definitely. I would still like to see more men test upstream hormones (LC/MS-MS) after using high enough doses of hCG at least 250-500IU injected EOD as such doses are most likely needed to fully restore physiological ITT levels. [URL unfurl="true"]https://www.discountedlabs.com/hormone-panel-for-men-on-trt-comprehensive[/URL] [URL unfurl="true"]https://www.discountedlabs.com/pregnenolone[/URL] [URL unfurl="true"]https://www.discountedlabs.com/progesterone[/URL] [URL unfurl="true"]https://www.discountedlabs.com/17-oh-progesterone-hcg-efficacy-predictor[/URL] [URL unfurl="true"]https://www.discountedlabs.com/dhea-sulfate[/URL] The goal should be to restore [I][B]physiological ITT levels[/B][/I] which may very well be needed to reap the full beneficial effects let alone to prevent disruption of upstream hormones! Unfortunately, many may struggle with sides on such protocol (dose/injection frequency). No point in stating/claiming that the addition of hCG has no impact on upstream hormones when you have never used high enough doses let alone tested using an accurate assay. [B]5.1 Effects on intratesticular testosterone [I]Exogenous testosterone administration suppresses intratesticular testosterone (ITT), which is crucial for the production of sperm [24]. [U]IN SUCH PATIENTS, ITT HAS BEEN SHOWN TO BE SUPPRESSED BY 94%[/U]. [U]However, with every other day injections of HCG at dosages of 125IU, ITT was only 25% LESS THAN BASELINE, with 250IU 7% LESS and with 500IU 26% GREATER THAN THE BASELINE[/U] [25]. *These studies indicate that HCG can significantly increase ITT in a dose-dependent manner and that [U]dosages between 250 and 500 IU might be optimal to restore physiological ITT levels[/U].[/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety?
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