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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety?
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<blockquote data-quote="madman" data-source="post: 203832" data-attributes="member: 13851"><p>I stated hCG mimics LH which stimulates Leydig cells leading to an increase in both ITT (intratesticular testosterone) and circulating testosterone levels.</p><p></p><p><strong><em>*LH is critical as it <u>stimulates cAMP production and cholesterol transport to and metabolism within mitochondria</u>.</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*<strong><em>LH plays two essential roles in Leydig cell steroidogenesis: (1) <u>maintenance of optimal levels of steroidogenic enzymes (trophic regulation) </u>and (2) <u>mobilization and transport of cholesterol into the inner mitochondrial membrane (acute regulation)</u>.</em></strong></em></strong></p><p></p><p></p><p>I was stressing the importance of LH/hCG/ITT especially when it comes to fertility/testicular atrophy!</p><p></p><p><em><strong>*To preserve/maintain fertility then yes.</strong></em></p><p><em><strong></strong></em></p><p><em><strong>*To prevent/minimize testicular atrophy then yes.</strong></em></p><p><em><strong></strong></em></p><p><em><strong>*<u>To enhance mood/libido than it is not a given </u>as some may experience such effects whereas others may feel worse-off.</strong></em></p><p></p><p><strong><em>*<u>To maintain upstream hormones and possibly prevent long-term consequences for health/well-being</u>.....you be the judge!</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 203832, member: 13851"] I stated hCG mimics LH which stimulates Leydig cells leading to an increase in both ITT (intratesticular testosterone) and circulating testosterone levels. [B][I]*LH is critical as it [U]stimulates cAMP production and cholesterol transport to and metabolism within mitochondria[/U]. *[B][I]LH plays two essential roles in Leydig cell steroidogenesis: (1) [U]maintenance of optimal levels of steroidogenic enzymes (trophic regulation) [/U]and (2) [U]mobilization and transport of cholesterol into the inner mitochondrial membrane (acute regulation)[/U].[/I][/B][/I][/B] I was stressing the importance of LH/hCG/ITT especially when it comes to fertility/testicular atrophy! [I][B]*To preserve/maintain fertility then yes. *To prevent/minimize testicular atrophy then yes. *[U]To enhance mood/libido than it is not a given [/U]as some may experience such effects whereas others may feel worse-off.[/B][/I] [B][I]*[U]To maintain upstream hormones and possibly prevent long-term consequences for health/well-being[/U].....you be the judge![/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety?
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