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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Trt-clomid-low shbg
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<blockquote data-quote="Cataceous" data-source="post: 279423" data-attributes="member: 38109"><p>I'm not sure about differences in estrone production between oral estradiol valerate and injections, but in general oral produces a lot more metabolites that affect blood clotting and such. So I would assign higher risk to oral.</p><p></p><p>With these extra metabolites it's plausible that oral would be more effective in raising SHBG; I have no idea if this is the case, however.</p><p></p><p>The half-life for oral is cited as 12-20 hours, so it's possible that sensitive individuals would notice the fluctuations.</p><p></p><p>I believe you could notice some differences in symptoms within a week or two, but a final evaluation should wait until after at least 6-8 weeks of treatment.</p><p></p><p>I don't recall hearing of estradiol causing breathlessness. I can speculate that an effect on fluid balance might indirectly lead to such sensations.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 279423, member: 38109"] I'm not sure about differences in estrone production between oral estradiol valerate and injections, but in general oral produces a lot more metabolites that affect blood clotting and such. So I would assign higher risk to oral. With these extra metabolites it's plausible that oral would be more effective in raising SHBG; I have no idea if this is the case, however. The half-life for oral is cited as 12-20 hours, so it's possible that sensitive individuals would notice the fluctuations. I believe you could notice some differences in symptoms within a week or two, but a final evaluation should wait until after at least 6-8 weeks of treatment. I don't recall hearing of estradiol causing breathlessness. I can speculate that an effect on fluid balance might indirectly lead to such sensations. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Trt-clomid-low shbg
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